6533b860fe1ef96bd12c3aae
RESEARCH PRODUCT
5-Amino-1-phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid
Giuseppe DaidoneMiriam RossiFrancesco CarusoMaria Valeria RaimondiClaudio Pettinarisubject
chemistry.chemical_classificationHydrogen bondDimerCarboxylic acidGeneral ChemistryPyrazoleDihedral angle010402 general chemistry010403 inorganic & nuclear chemistryCondensed Matter PhysicsBioinformaticsOrganic Papers01 natural sciencesMedicinal chemistry3. Good health0104 chemical sciencesCrystallcsh:Chemistrychemistry.chemical_compoundchemistrylcsh:QD1-999X-ray studyGeneral Materials Sciencedescription
In the title compound, C11H8F3N3O2, there are two molecules in the asymmetric unit wherein the phenyl rings make dihedral angles of 65.3 (2) and 85.6 (2)° with the pyrazole rings. In the crystal, pairs of molecules are held together by O—H...O hydrogen bonds between the carboxyl groups, forming a centrosymmetric dimer with an R22(8) motif. Intramolecular N—H...O interactions are also present.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-01-01 | Acta Crystallographica Section E |