0000000001145183
AUTHOR
Marie-chantal Canivenc
Impairment of learning and memory performances induced by BPA Evidences from the literature of a MoA mediated through an ED
International audience; Many rodent studies and a few non-human primate data report impairments of spatial and non-spatial memory induced by exposure to bisphenol A (BPA), which are associated with neural modifications, particularly in processes involved in synaptic plasticity. BPA-induced alterations involve disruption of the estrogenic pathway as established by reversal of BPA-induced effects with estrogenic receptor antagonist or by interference of BPA with administered estradiol in ovariectomized animals. Sex differences in hormonal impregnation during critical periods of development and their influence on maturation of learning and memory processes may explain the sexual dimorphism obs…
Impact of perinatal over-nutrition on the developing sweet/fatty taste and the ontogeny of brain reward pathway, from birth to sexual maturity in rat
National audience
Perinatal Western Diet consumption leads to a profound change in plasticity and GABAergic phenotype within hypothalamus and reward pathway from birth to sexual maturity in rat
National audience