0000000001149240
AUTHOR
P. Greco
Celiac disease and selective immunoglobulin A deficiency
Selective IgA deficiency was observed in 12 of 688 (1.7%) patients with celiac disease who were clinically undistinguishable from patients with celiac disease with normal IgA levels. This high prevalence of IgA deficiency in patients with celiac disease makes serum IgA assay advisable when screening for celiac disease is performed by measurement of antigliadin antibodies or anti-IgA endomysium antibodies. Similarly, subjects with IgA deficiency should be considered at risk of celiac disease.
Platelet count does not predict bleeding in cirrhotic patients: Results from the PRO-LIVER Study
OBJECTIVES: Thrombocytopenia is a hallmark for patients with cirrhosis and it is perceived as a risk factor for bleeding events. However, the relationship between platelet count and bleeding is still unclear. METHODS: We investigated the relationship between platelet count and major or clinical relevant nonmajor bleedings during a follow-up of â¼4 years. RESULTS: A total of 280 cirrhotic patients with different degrees of liver disease (67% males; age 64±37 years; 47% ChildâPugh B and C) were followed up for a median of 1,129 (interquartile range: 800â1,498) days yielding 953.12 patient-year of observation. The annual rate of any significant bleeding was 5.45%/year (3.57%/year and 1.8…
MEMORIA E PROGETTO Un modello per il Mezzogiorno che serva a tutto il Paese
DALLA QUARTA DI COPERTINA DEL VOLUME: L’Italia, è stato detto di recente, è un paese senza bussola. Ha perso la memoria del suo futuro. Le manca un progetto. Persino la sua tenuta come nazione, a centocinquant’anni dalla raggiunta unità, è messa in dubbio. Occorre un progetto. Per il Sud e per tutto il Paese. A quarant’anni dalla fondazione dell’Istituto di Cibernetica del CNR a opera di Eduardo Caianiello, gli autori del libro colgono “l’occasione non solo per ricordare il passato e proporre un consuntivo dell’attività svolta, ma anche per recuperare la ‘memoria del futuro’ e costruire un progetto, alla luce delle intuizioni dello scienziato napoletano. Eduardo Caianiello è il fisico che h…