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RESEARCH PRODUCT
Celiac disease and selective immunoglobulin A deficiency
V MarinoG BottaroP. GrecoFrancesco CataldoAlessandro Venturasubject
AdolescentGlutensCross-sectional studyMuscle Fibers SkeletalDiseaseSelective IgA deficiencyImmunoglobulin EGliadinCoeliac diseaseMyofibrilsRisk FactorsImmunopathologyConfidence IntervalsDiet Protein-RestrictedPrevalencemedicineHumansChildChi-Square Distributionbiologybusiness.industryAge FactorsIgA DeficiencyInfantnutritional and metabolic diseasesmedicine.diseaseEndomysiumdigestive system diseasesImmunoglobulin ACeliac DiseaseIntestinal DiseasesCross-Sectional Studiesmedicine.anatomical_structureImmunoglobulin MChild PreschoolImmunoglobulin GPediatrics Perinatology and Child HealthImmunologybiology.proteinAntibodybusinessFollow-Up Studiesdescription
Selective IgA deficiency was observed in 12 of 688 (1.7%) patients with celiac disease who were clinically undistinguishable from patients with celiac disease with normal IgA levels. This high prevalence of IgA deficiency in patients with celiac disease makes serum IgA assay advisable when screening for celiac disease is performed by measurement of antigliadin antibodies or anti-IgA endomysium antibodies. Similarly, subjects with IgA deficiency should be considered at risk of celiac disease.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1997-08-01 | The Journal of Pediatrics |