Author: Nicolò Tirone

0000000001153740

AUTHOR

Nicolò Tirone

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Effects of Polycyclic Aromatic Hydrocarbons on Lung Function in Children with Asthma: A Mediation Analysis.

2022

Studies investigating the association between urinary Polycyclic Aromatic Hydrocarbons (PAHs) and asthma in children provided inhomogeneous results. We aimed to use Mediation Analysis to discover whether a link between urinary PAHs and lung function exists and if it might be ascribed to a direct or a symptom-mediated (indirect) effect in children with asthma. This single-center prospective study was conducted in Palermo, Italy, between March and July 2017 and involved 50 children with persistent mild-moderate asthma, aged 6–11 years. At each time visit (day 0, 30, 60, and 90), physical examination, spirometry, and urine collection for detection of urinary cotinine and PAHs were performed. A…

Mediation AnalysisHealth Toxicology and MutagenesisPublic Health Environmental and Occupational HealthRAmbientalelung functionpolycyclic aromatic hydrocarbons lung function children asthma mediation analysisAsthmapolycyclic aromatic hydrocarbons; lung function; children; asthma; mediation analysischildrenMedicineHumansProspective StudiesPolycyclic Aromatic HydrocarbonsChildAsthma Children Lung function Mediation analysis Polycyclic aromatic hydrocarbons Child Humans Lung Mediation Analysis Prospective Studies Asthma Polycyclic Aromatic Hydrocarbonsasthma children lung function mediation analysis polycyclic aromatic hydrocarbonsLungInternational journal of environmental research and public health

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