0000000001162689

AUTHOR

Melinda Cservenák

0000-0002-6899-9944

showing 1 related works from this author

Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome

2018

Abstract It has been suggested that exercise training and probiotic supplementation could decelerate the progress of functional and biochemical deterioration in APP/PS1 transgenic mice (APP/PS1TG). APP/PS1TG mice were subjected to exercise training and probiotic treatments and functional, biochemical and microbiome markers were analyzed. Under these conditions the mice significantly outperformed controls on The Morris Maze Test, and the number of beta-amyloid plaques decreased in the hippocampus. B. thetaiotaomicron levels correlated highly with the results of the Morris Maze Test (p

Male0301 basic medicineGenetically modified mouseAgingalzheimer; exercise; microbiome; probioticsalzheimermicrobiomeMice TransgenicPlaque AmyloidDiseaseHippocampusBiochemistrylaw.inventionAmyloid beta-Protein PrecursorMice03 medical and health sciencesProbiotic0302 clinical medicineEndocrinologyAlzheimer DiseaselawPhysical Conditioning Animalmental disordersPresenilin-1GeneticsAnimalsHippocampus (mythology)MedicineMicrobiomeMolecular BiologyAmyloid beta-Peptidesexercisebusiness.industryMicrobiotaCell BiologyDisease Models Animal030104 developmental biologyprobioticsImmunologybusiness030217 neurology & neurosurgeryExperimental Gerontology
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