Evidence for the decay X(3872)→ψ(2S)γ

2014

Evidence for the decay mode X(3872) -> psi(2S)gamma in B+ -> X(3872)K+ decays is found with a significance of 4.4 standard deviations. The analysis is based on a data sample of proton proton collisions, corresponding to an integrated luminosity of 3 fb(-1), collected with the LHCb detector, at centre-of-mass energies of 7 and 8 TeV. The ratio of the branching fraction of the X(3872) -> psi(2S)gamma decay to that of the X(3872) -> J/psi gamma decay is measured to be B(X(3872) -> psi(2S)gamma)/B(X(3872) -> J/psi gamma) = 2.46 +/- 0.64 +/- 0.29, where the first uncertainty is statistical and the second is systematic. The measured value does not support a pure D (D) over bar* molecular interpre…

First observation of a baryonic Bc+ decay

2014

A baryonic decay of the $B_c^+$ meson, $B_c^+\to J/\psi p\overline{p}\pi^+$, is observed for the first time, with a significance of $7.3$ standard deviations, in $pp$ collision data collected with the LHCb detector and corresponding to an integrated luminosity of $3.0$ fb$^{-1}$ taken at center-of-mass energies of $7$ and $8$ $\mathrm{TeV}$. With the $B_c^+\to J/\psi \pi^+$ decay as normalization channel, the ratio of branching fractions is measured to be \begin{equation*} \frac{\mathcal{B}(B_c^+\to J/\psi p\overline{p}\pi^+)}{\mathcal{B}(B_c^+\to J/\psi \pi^+)} = 0.143^{\,+\,0.039}_{\,-\,0.034}\,(\mathrm{stat})\pm0.013\,(\mathrm{syst}). \end{equation*} The mass of the $B_c^+$ meson is dete…

Precision measurement of the ratio of the Λb0 to B¯0 lifetimes

2014

The LHCb measurement of the lifetime ratio of the Lambda(0)(b) baryon to the (B) over bar (0) meson is updated using data corresponding to an integrated luminosity of 3.0 fb(-1) collected using 7 and 8 TeV centre-of-mass energy pp collisions at the LHC. The decay modes used are Lambda(0)(b) -> J/psi pK(-) and (B) over bar (0) -> J/psi pi K-+(-), where the pi K-+(-) mass is consistent with that of the (K) over bar*(0)(892) meson. The lifetime ratio is determined with unprecedented precision to be 0.974 +/- 0.006 +/- 0.004, where the first uncertainty is statistical and the second systematic. This result is in agreement with original theoretical predictions based on the heavy quark expansion.…

Measurement of the resonant andCPcomponents inB¯0→J/ψπ+π−decays

2014

The resonant structure of the reaction (B) over bar (0) --> J/psi pi(+)pi(-) is studied using data from 3 fb(-1) of integrated luminosity collected by the LHCb experiment, one third at 7 TeV center-of-mass energy and the remainder at 8 TeV. The invariant mass of the pi(+)pi(-) pair and three decay angular distributions are used to determine the fractions of the resonant and nonresonant components. Six interfering pi(+)pi(-) states, rho(770), f(0)(500), f(2)(1270), rho(1450), omega(782) and rho(1700), are required to give a good description of invariant mass spectra and decay angular distributions. The positive and negative charge parity fractions of each of the resonant final states are det…

Measurement of theB¯s0Meson Lifetime inDs+π−Decays

2014

The first measurement of the effective lifetime of the (B) over bar (o)(s) meson in the decay (B) over bar (o)(s) -> D-s(-) D-s(+) is reported using a proton-proton collision data set, corresponding to an integrated luminosity of 3 fb(-1), collected by the LHCb experiment. The measured value of the (B) over bar (o)(s) -> D-s(-) D-s(+) effective lifetime is 1.379 +/- 0.026 +/- 0.017 ps, where the uncertainties are statistical and systematic, respectively. This lifetime translates into a measurement of the decay width of the light (B) over bar (o)(s) mass eigenstate of Gamma(L) 0.725 +/- 0.014 +/- 0.009 ps(-1). The (B) over bar (o)(s) lifetime is also measured using the flavor-specific (B) ov…

First Observation of Top Quark Production in the Forward Region

2015

Top quark production in the forward region in proton-proton collisions is observed for the first time. The W + b final state with W → μν is reconstructed using muons with a transverse momentum, p[subscript T], larger than 25 GeV in the pseudorapidity range 2.0 20  GeV. The results are based on data corresponding to integrated luminosities of 1.0 and 2.0  fb[superscript -1] collected at center-of-mass energies of 7 and 8 TeV by LHCb. The inclusive top quark production cross sections in the fiducial region are σ(top)[7  TeV] = 239 ± 53(stat) ± 33(syst) ± 24(theory)  fb, σ(top)[8  TeV] = 289 ± 43(stat) ± 40(syst) ± 29(theory)  fb.These results, along with the observed differential yields and c…

Precision measurement of D meson mass differences

2013

Using three- and four-body decays of D mesons produced in semileptonic b-hadron decays, precision measurements of D meson mass differences are made together with a measurement of the D-0 mass. The measurements are based on a dataset corresponding to an integrated luminosity of 1.0 fb(-1) collected in pp collisions at 7 TeV. Using the decay D-0 -> K+K-K-pi(+), the D-0 mass is measured to be M(D-0) = 1864.75 +/- 0.15 (stat) +/- 0.11 (syst) MeV/c(2). The mass differences M(D+) - M(D-0) = 4.76 +/- 0.12 (stat) +/- 0.07 (syst) MeV/c(2), M(D-s(+)) - M(D+) = 98.68 +/- 0.03 (stat) +/- 0.04 (syst) MeV/c(2) are measured using the D-0 -> K+K-pi(+)pi(-) and D-(s)(+) -> K+K-pi(+) modes.

Functional relevance and diagnostic utility of ROI-based and voxel-based diffusion-tensor imaging analyses in mild cognitive impairment

2007

Study of W Boson Production in Association with Beauty and Charm

2015

The associated production of a W boson with a jet originating from either a light parton or heavy-flavor quark is studied in the forward region using proton-proton collisions. The analysis uses data corresponding to integrated luminosities of 1.0 and 2.0  fb[superscript -1] collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV, respectively. The W bosons are reconstructed using the W → μν decay and muons with a transverse momentum, p[subscript T], larger than 20 GeV in the pseudorapidity range 2.0 20  GeV and 2.2 20  GeV. The fraction of W + jet events that originate from beauty and charm quarks is measured, along with the charge asymmetries of the W + b and W + c produ…

Measurement of the chi(b) (3 P) mass and of the relative rate of chi(b1) (1 P) and chi(b2) (1 P) production

2014

The production of $\chi_b$ mesons in proton-proton collisions is studied using a data sample collected by the LHCb detector, at centre-of-mass energies of $\sqrt{s}=7$ and $8$ TeV and corresponding to an integrated luminosity of 3.0 fb$^{-1}$. The $\chi_b$ mesons are identified through their decays to $\Upsilon(1S)\gamma$ and $\Upsilon(2S)\gamma$ using photons that converted to $e^+e^-$ pairs in the detector. The $\chi_b(3P)$ meson mass, and the relative prompt production rate of $\chi_{b1}(1P)$ and $\chi_{b2}(1P)$ mesons as a function of the $\Upsilon(1S)$ transverse momentum in the $\chi_b$ rapidity range 2.0< $y$<4.5, are measured. Assuming a mass splitting between the $\chi_{b1}(3P)$ an…

Observation of charmonium pairs produced exclusively in $pp$ collisions

2014

A search is performed for the central exclusive production of pairs of charmonia produced in proton-proton collisions. Using data corresponding to an integrated luminosity of $3{\rm\ fb}^{-1}$ collected at centre-of-mass energies of 7 and 8 TeV, $J/\psi J/\psi$ and $J/\psi\psi(2S)$ pairs are observed, which have been produced in the absence of any other activity inside the LHCb acceptance that is sensitive to charged particles in the pseudorapidity ranges $(-3.5,-1.5)$ and $(1.5,5.0)$. Searches are also performed for pairs of P-wave charmonia and limits are set on their production. The cross-sections for these processes, where the dimeson system has a rapidity between 2.0 and 4.5, are measu…

Measurement of CP asymmetry in D 0 → K - K + and D 0 → π - πdecays

2014

Time-integrated $CP$ asymmetries in $D^0$ decays to the final states $K^- K^+$ and $\pi^- \pi^+$ are measured using proton-proton collisions corresponding to $3\mathrm{\,fb}^{-1}$ of integrated luminosity collected at centre-of-mass energies of $7\mathrm{\,Te\kern -0.1em V}$ and $8\mathrm{\,Te\kern -0.1em V}$. The $D^0$ mesons are produced in semileptonic $b$-hadron decays, where the charge of the accompanying muon is used to determine the initial flavour of the charm meson. The difference in $CP$ asymmetries between the two final states is measured to be \begin{align} \Delta A_{CP} = A_{CP}(K^-K^+)-A_{CP}(\pi^-\pi^+) = (+0.14 \pm 0.16\mathrm{\,(stat)} \pm 0.08\mathrm{\,(syst)})\% \ . \nonu…

Observation of charmless baryonic decays B(s)0→pp¯h+h′−

2017

Decays of B0 and Bs0 mesons to the charmless baryonic final states pp¯h+h′-, where h and h′ each denote a kaon or a pion, are searched for using the LHCb detector. The analysis is based on a sample of proton-proton collision data collected at center-of-mass energies of 7 and 8 TeV, corresponding to an integrated luminosity of 3  fb-1. Four-body charmless baryonic Bs0 decays are observed for the first time. The decays Bs0→pp¯K+K-, Bs0→pp¯K±π∓, B0→pp¯K±π∓ and B0→pp¯π+π- are observed with a significance greater than 5 standard deviations; evidence at 4.1 standard deviations is found for the B0→pp¯K+K- decay and an upper limit is set on the branching fraction for Bs0→pp¯π+π-. Branching fraction…

Measurement of CP asymmetry in Bs0 → Ds ∓K± decays

2014

Journal of high energy physics 2018(3), 59 (2018). doi:10.1007/JHEP03(2018)059

First observation and amplitude analysis of theB−→D+K−π−decay

2015

The B- -> D+K-pi(-) decay is observed in a data sample corresponding to 3.0 fb(-1) of pp collision data recorded by the LHCb experiment during 2011 and 2012. Its branching fraction is measured to be B(B- -> D+K-pi(-)) = (7.31 +/- 0.19 +/- 0.22 +/- 0.39) x 10(-5) where the uncertainties are statistical, systematic and from the branching fraction of the normalization channel B- -> D+pi(-)pi(-), respectively. An amplitude analysis of the resonant structure of the B- -> D+K-pi(-) decay is used to measure the contributions from quasi-two-body B- -> D-0* (2400)K-0(-), B- -> D-2* (2460)K-0(-), and B- -> D-J* (2760)K-0(-) decays, as well as from nonresonant sources. The D-J* (2760)(0) resonance is …

Measurement of the lifetime of theBc+meson using theBc+→J/ψπ+decay mode

2015

The difference in total widths between the B+c and B+ mesons is measured using 3.0fb−1 of data collected by the LHCb experiment in 7 and 8 TeV centre-of-mass energy proton-proton collisions at the LHC. Through the study of the time evolution of B+c→J/ψπ+ and B+→J/ψK+ decays, the width difference is measured to beΔΓ≡ΓB+c−ΓB+=4.46±0.14±0.07mm−1c,where the first uncertainty is statistical and the second systematic. The known lifetime of the B+ meson is used to convert this to a precise measurement of the B+c lifetime,τB+c=513.4±11.0±5.7fs,where the first uncertainty is statistical and the second systematic.

Search for CP violation inD0→π−π+π0decays with the energy test

2015

A search for time-integrated CP violation in the Cabibbo-suppressed decay D-0 -> pi(-)pi(+)pi(0) ir is performed using for the first time an unbinned model-independent technique known as the energy test. Using proton-proton collision data, corresponding to an integrated luminosity of 2.0 fb(-1) collected by the LHCb detector at a centre-of-mass energy of root s = 8 TeV, the world's best sensitivity to CP violation in this decay is obtained. The data are found to be consistent with the hypothesis of CP symmetry with a p-value of (2.6 +/- 0.5)%. (C) 2014 The Authors. Published by Elsevier B.V.

Observation of $Z$ production in proton-lead collisions at LHCb

2014

The first observation of $Z$ boson production in proton-lead collisions at a centre-of-mass energy per proton-nucleon pair of $\sqrt{s_{NN}}=5~\text{TeV}$ is presented. The data sample corresponds to an integrated luminosity of $1.6~\text{nb}^{-1}$ collected with the LHCb detector. The $Z$ candidates are reconstructed from pairs of oppositely charged muons with pseudorapidities between 2.0 and 4.5 and transverse momenta above $20~\text{GeV}/c$. The invariant dimuon mass is restricted to the range $60-120~\text{GeV}/c^2$. The $Z$ production cross-section is measured to be \begin{eqnarray*} ��_{Z\to��^+��^-}(\text{fwd})&amp;=&amp;13.5^{+5.4}_{-4.0}\text{(stat.)}\pm1.2\text{(syst.)}~\text{nb} …

Differential branching fractions and isospin asymmetries of B -> K ((*)) μ(+) μ(-) decays

2014

The isospin asymmetries of $B \to K\mu^+\mu^-$ and $B \to K^{*}\mu^+\mu^-$ decays and the partial branching fractions of the $B^0 \to K^0\mu^+\mu^-$, $B^+ \to K^+\mu^+\mu^-$ and $B^+ \to K^{*+}\mu^+\mu^-$ decays are measured as functions of the dimuon mass squared, $q^2$. The data used correspond to an integrated luminosity of 3$~$fb$^{-1}$ from proton-proton collisions collected with the LHCb detector at centre-of-mass energies of 7$\,$TeV and 8$\,$TeV in 2011 and 2012, respectively. The isospin asymmetries are both consistent with the Standard Model expectations. The three measured branching fractions, while individually consistent, all favour lower values than their respective Standard M…

Study of the rare Bs0 and B0 decays into the π+π−μ+μ− final state

2015

A search for the rare decays B0s→π+π−μ+μ− and B0→π+π−μ+μ− is performed in a data set corresponding to an integrated luminosity of 3.0 fb−1 collected by the LHCb detector in proton-proton collisions at centre-of-mass energies of 7 and 8 TeV. Decay candidates with pion pairs that have invariant mass in the range 0.5-1.3 GeV/c2 and with muon pairs that do not originate from a resonance are considered. The first observation of the decay B0s→π+π−μ+μ− and the first evidence of the decay B0→π+π−μ+μ− are obtained and the branching fractions are measured to be B(B0s→π+π−μ+μ−)=(8.6±1.5(stat)±0.7(syst)±0.7(norm))×10−8 and B(B0→π+π−μ+μ−)=(2.11±0.51(stat)±0.15(syst)±0.16(norm))×10−8, where the third unc…

Effective lifetime measurements in theBs0→K+K−,B0→K+π−andBs0→π+K−decays

2014

Measurements of the effective lifetimes in the B-s(0) -> K+K-, B-0 -> K+pi(-) and B-s(0) -> pi K-+(-) decays are presented using 1.0 fb(-1)of pp collision data collected at a centre-of-mass energy of 7 TeV by the LHCb experiment. The analysis uses a data-driven approach to correct for the decay time acceptance. The measured effective lifetimes are tau(Bs0 -> K+K-) = 1.407 +/- 0.016 (stat) +/- 0.007 (syst) ps, tau(Bs0 -> K+pi-) = 1.524 +/- 0.011 (stat) +/- 0.004 (syst) ps, tau(Bs0 ->pi+K-) = 1.60 +/- 0.06 (stat) +/- 0.01 (syst) ps. This is the most precise determination to date of the effective lifetime in the B-s(0) -> K+K- decay and provides constraints on contributions from physics beyond…

Precision Measurement ofCPViolation inBS0→J/ΨK+K−Decays

2015

The time-dependent CP asymmetry in B-S(0) -> J/Psi K+K- decays is measured using pp collision data, corresponding to an integrated luminosity of 3.0 fb(-1), collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV. In a sample of 96 000 B-S(0) -> J/Psi K+K- decays, the CP-violating phase phi(s) is measured, as well as the decay widths GL and GH of the light and heavy mass eigenstates of the B-s(0)-(B) over bar (0)(s) system. The values obtained are phi(s) = -0.058 +/- 0.049 +/- 0.006 rad, Gamma(s) equivalent to (Gamma(L) + Gamma(H))/2 = 0.6603 +/- 0.0027 +/- 0.0015 ps(-1), and Delta Gamma(s) equivalent to Gamma(L)-Gamma(H) = 0.0805 +/- 0.0091 +/- 0.0032 ps(-1), where the f…

Differential branching fraction and angular analysis of the decay $B^{0} \to K^{*0} \mu^{+}\mu^{-}$

2013

The angular distribution and differential branching fraction of the decay B-0 -> K*(0)mu(+)mu(-) are studied using a data sample, collected by the LHCb experiment in pp collisions at root s = 7 TeV, corresponding to an integrated luminosity of 1.0 fb(-1). Several angular observables are measured in bins of the dimuon invariant mass squared, q(2). A first measurement of the zero-crossing point of the forward-backward asymmetry of the dimuon system is also presented. The zero-crossing point is measured to be q(0)(2) = 4.9 +/- 0.9 GeV2/c(4), where the uncertainty is the sum of statistical and systematic uncertainties. The results are consistent with the Standard Model predictions.

Neuropsychiatric symptoms and brain structural alterations in Fabry disease

2010

Background:  Neuropsychiatric symptoms (NPS), mainly cognitive deficits up to dementia and depressive syndromes have been described repeatedly in Fabry disease (FD). However, examinations regarding the pattern, extent, and frequency of the NPS in FD are still lacking. Moreover, the relationship between NPS and brain structural alterations in FD is unknown. The aim of this study was 1) to characterize NPS in a relatively large cohort of adult subjects with FD, and 2) to explore the association of cognitive performance and depressive syndromes with the FD-typical brain structural findings. Methods:  Twenty-five Fabry patients (age 36.5 ± 11.0) with mild to moderate disease involvement and 20 …

Measurement of the branching fraction of the decay Bs0→KS0KS0

2020

A measurement of the branching fraction of the decay Bs0→KS0KS0 is performed using proton-proton collision data corresponding to an integrated luminosity of 5 fb-1 collected by the LHCb experiment between 2011 and 2016. The branching fraction is determined to be B(Bs0→KS0KS0)=[8.3±1.6(stat)±0.9(syst)±0.8(norm)±0.3(fs/fd)]×10-6, where the first uncertainty is statistical, the second is systematic, and the third and fourth are due to uncertainties on the branching fraction of the normalization mode B0→φKS0 and the ratio of hadronization fractions fs/fd. This is the most precise measurement of this branching fraction to date. Furthermore, a measurement of the branching fraction of the decay B0…

Oxygen and glucose deprivation induces major dysfunction in the somatosensory cortex of the newborn rat

2005

The mechanisms and functional consequences of ischemia-induced injury during perinatal development are poorly understood. Subplate neurons (SPn) play a central role in early cortical development and a pathophysiological impairment of these neurons may have long-term detrimental effects on cortical function. The acute and long-term consequences of combined oxygen and glucose deprivation (OGD) were investigated in SPn and compared with OGD-induced dysfunction of immature layer V pyramidal cortical neurons (PCn) in somatosensory cortical slices from postnatal day (P)0-4 rats. OGD for 50 min followed by a 10-24-h period of normal oxygenation and glucose supply in vitro or in culture led to pron…

Observation of Photon Polarization in theb→sγTransition

2014

This Letter presents a study of the flavor-changing neutral current radiative $B^{\pm} \to K^{\pm}\pi^{\mp}\pi^{\pm}\gamma$ decays performed using data collected in proton-proton collisions with the LHCb detector at $7$ and $8\,$TeV center-of-mass energies. In this sample, corresponding to an integrated luminosity of $3\,\text{fb}^{-1}$, nearly $14\,000$ signal events are reconstructed and selected, containing all possible intermediate resonances with a $K^{\pm}\pi^{\mp}\pi^{\pm}$ final state in the $[1.1, 1.9]\,$GeV/$c^{2}$ mass range. The distribution of the angle of the photon direction with respect to the plane defined by the final-state hadrons in their rest frame is studied in interva…

Searches for violation of lepton flavour and baryon number in tau lepton decays at LHCb

2013

Searches for the lepton flavour violating decay tau(-) -> mu(-)mu(+)mu(-) and the lepton flavour and baryon number violating decays tau(-) -> (p) over bar mu(+)mu(-) and tau(-) -> p mu(-)mu(-) have been carried out using proton-proton collision data, corresponding to an integrated luminosity of 1.0 fb(-1), taken by the LHCb experiment at root s = 7 TeV. No evidence has been found for any signal, and limits have been set at 90% confidence level on the branching fractions: B(tau(-) -> mu(-)mu(+)mu(-) mu(+)mu(-)) p mu(-)mu(-)) (p) over bar mu(+)mu(-) and tau(-) -> p mu(-)mu(-) decay modes represent the first direct experimental limits on these channels.

Functional relevant loss of long association fibre tracts integrity in early Alzheimer's disease.

2007

Abstract The aim of our study was to quantify the structural integrity of the long association fibre tracts in early Alzheimer's disease (AD) and to correlate the findings with the cognitive performance of the patients. We conducted region-of-interest-based analyses of color-coded diffusion-tensor imaging in 12 patients with early AD (age 69.8 ± 8.0 years; MMSE 25.3 ± 1.8) and 16 age- and education-matched healthy controls. Early AD patients showed significantly decreased fractional anisotropy (FA) of the cingulate bundles and the inferior fronto-occipital fascicles bilaterally, whereas FA values of the superior longitudinal fascicles (second division) did not differ significantly between p…

Study ofCPviolation inB∓→Dh∓(h=K,π) with the modesD→K∓π±π0,D→π+π−π0andD→K+K−π0

2015

An analysis of the decays of B--/+ -> DK -/+ and B--/+ -> D pi(-/+) is presented in which the D meson is reconstructed in the three-body final states K--/+pi(+/-)pi(0), pi(+)pi(-)pi(0) and K+K-pi(0). Using data from LHCb corresponding to an integrated luminosity of 3.0 fb(-1) of pp collisions, measurements of several CP observables are performed. First observations are obtained of the suppressed Atwood-Dunietz-Soni decay B--/+ -> [pi K-+(+/-)pi(0)](D)pi(-/+) and the quasi-Gronau-London-Wyler decay B--/+ -> [K+K-pi(0)](D)pi(-/+). The results are interpreted in the context of the unitarity triangle angle gamma and related parameters.

Precision Measurement of the Mass and Lifetime of the Ξ[0 over b] Baryon

2014

Using a proton-proton collision data sample corresponding to an integrated luminosity of 3 fb$^{-1}$ collected by LHCb at center-of-mass energies of 7 and 8 TeV, about 3800 $\Xi_b^0\to\Xi_c^+\pi^-$, $\Xi_c^+\to pK^-\pi^+$ signal decays are reconstructed. From this sample, the first measurement of the $\Xi_b^0$ baryon lifetime is made, relative to that of the $\Lambda_b^0$ baryon. The mass differences $M(\Xi_b^0)-M(\Lambda_b^0)$ and $M(\Xi_c^+)-M(\Lambda_c^+)$ are also measured with precision more than four times better than the current world averages. The resulting values are $\frac{\tau_{\Xi_b^0}}{\tau_{\Lambda_b^0}} = 1.006\pm0.018\pm0.010$, $M(\Xi_b^0) - M(\Lambda_b^0) = 172.44\pm0.39\pm…

Brain structural alterations in Fabry disease: ROI-based and voxel-based analyses of diffusion tensor imaging parameters

2007

Measurement of CP asymmetries in the decays B0 → K*0 μ+μ- and B+ → K+ μ+μ-

2014

The direct CP asymmetries of the decays B 0 → K *0 μ + μ − and B + → K + μ + μ − are measured using pp collision data corresponding to an integrated luminosity of 3.0 fb−1 collected with the LHCb detector. The respective control modes B 0 → J/ψK *0 and B + → J/ψK + are used to account for detection and production asymmetries. The measurements are made in several intervals of μ + μ − invariant mass squared, with the ϕ(1020) and charmonium resonance regions excluded. Under the hypothesis of zero CP asymmetry in the control modes, the average values of the asymmetries are ACP(B0→K∗0μ+μ−)=−0.035±0.024±0.003,ACP(B+→K+μ+μ−)=0.012±0.017±0.001, where the first uncertainties are statistical and the …

Voxel based analyses of diffusion tensor imaging in Fabry disease

2007

Background: Fabry disease (FD) is a lysosomal storage disorder that is associated with marked cerebrovascular disease. Conventional MRI shows an extensive load of white matter lesions (WMLs) already at an early stage in FD. Objective: Investigator independent and sensitive quantification of brain structural changes in clinically affected men and women with FD. Methods: The authors performed a voxel-based analysis of diffusion tensor images (DTI) in 25 FD patients and 20 age-matched normal controls. Results: DTI revealed significant increases of cerebral white matter diffusivity (MD) in FD patients that were pronounced in the periventricular white matter. Even the subgroup of patients withou…

Determination of the $X(3872)$ meson quantum numbers

2013

The quantum numbers of the X(3872) meson are determined to be J(PC) = 1(++) based on angular correlations in B+ -> X(3872)K+ decays, where X(3872) -> pi(+) pi(-) j/psi and J/psi -> pi(+) mu(-). The data correspond to 1.0 fb(-1) of pp collisions collected by the LHCb detector. The only alternative assignment allowed by previous measurements J(PC) = 2(-+) is rejected with a confidence level equivalent to more than 8 Gaussian standard deviations using a likelihood-ratio test in the full angular phase space. This result favors exotic explanations of the X(3872) state.

Search for CP violation using T-odd correlations in D-0 -> K+K-pi(+)pi(-) decays

2014

A search for $CP$ violation using $T$-odd correlations is performed using the four-body $D^0 \to K^+K^-\pi^+\pi^-$ decay, selected from semileptonic $B$ decays. The data sample corresponds to integrated luminosities of $1.0\,\text{fb}^{-1}$ and $2.0\,\text{fb}^{-1}$ recorded at the centre-of-mass energies of 7 TeV and 8 TeV, respectively. The $CP$-violating asymmetry $a_{CP}^{T\text{-odd}}$ is measured to be $(0.18\pm 0.29\text{(stat)}\pm 0.04\text{(syst)})\%$. Searches for $CP$ violation in different regions of phase space of the four-body decay, and as a function of the $D^0$ decay time, are also presented. No significant deviation from the $CP$ conservation hypothesis is found.

FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin…

2010

EPIC-3 is a prospective, international study that has demonstrated the efficacy of PEG-IFN alfa-2b plus weight-based ribavirin in patients with chronic hepatitis C and significant fibrosis who previously failed any interferon-alfa/ribavirin therapy. The aim of the present study was to assess FibroTest (FT), a validated non-invasive marker of fibrosis in treatment-naive patients, as a possible alternative to biopsy as the baseline predictor of subsequent early virologic (EVR) and sustained virologic response (SVR) in previously treated patients.Of 2312 patients enrolled, 1459 had an available baseline FT, biopsy, and complete data. Uni- (UV) and multi-variable (MV) analyses were performed us…

Measurement of the ratio ofBc+branching fractions toJ/ψπ+andJ/ψμ+νμfinal states

2014

The first measurement that relates semileptonic and hadronic decay rates of the B-c(+) meson is performed using proton-proton collision data corresponding to 1.0 fb(-1) of integrated luminosity collected with the LHCb detector. The measured value of the ratio of branching fractions, B(B-c(+) -> J/psi pi(+))/B(B-c(+) -> J/psi mu(+)nu(mu)) = 0.0469 +/- 0.0028(stat) +/- 0.0046(syst), is at the lower end of available theoretical predictions.

First study of the CP-violating phase and decay-width difference in Bs0→ψ(2S)ϕ decays

2016

A time-dependent angular analysis of Bs0→ψ(2S)ϕ decays is performed using data recorded by the LHCb experiment. The data set corresponds to an integrated luminosity of 3.0fb−1 collected during Run 1 of the LHC. The CP-violating phase and decay-width difference of the Bs0 system are measured to be ϕs=0.23−0.28+0.29±0.02rad and ΔΓs=0.066−0.044+0.041±0.007ps−1, respectively, where the first uncertainty is statistical and the second systematic. This is the first time that ϕs and ΔΓs have been measured in a decay containing the ψ(2S) resonance.

Observation of Two NewΞb−Baryon Resonances

2015

Two structures are observed close to the kinematic threshold in the Ξb0π- mass spectrum in a sample of proton-proton collision data, corresponding to an integrated luminosity of 3.0fb-1, recorded by the LHCb experiment. In the quark model, two baryonic resonances with quark content bds are expected in this mass region: the spin-parity JP=(1/2)+ and JP=(3/2)+ states, denoted Ξb′- and Ξb∗-. Interpreting the structures as these resonances, we measure the mass differences and the width of the heavier state to be m(Ξb′-)-m(Ξb0)-m(π-)=3.653±0.018±0.006MeV/c2, m(Ξb∗-)-m(Ξb0)-m(π-)=23.96±0.12±0.06MeV/c2, Γ(Ξb∗-)=1.65±0.31±0.10MeV, where the first and second uncertainties are statistical and systema…

Measurements of charm mixing and CP violation using D0→K±π∓ decays

2017

Measurements of charm mixing and CP violation parameters from the decay-time-dependent ratio of D0→K+π− to D0→K−π+ decay rates and the charge-conjugate ratio are reported. The analysis uses B¯¯¯¯→D∗+μ−X, and charge-conjugate decays, where D∗+→D0π+, and D0→K∓π±. The pp collision data are recorded by the LHCb experiment at center-of-mass energies s√ = 7 and 8 TeV, corresponding to an integrated luminosity of 3 fb−1. The data are analyzed under three hypotheses: (i) mixing assuming CP symmetry, (ii) mixing assuming no direct CP violation in the Cabibbo-favored or doubly Cabibbo-suppressed decay amplitudes, and (iii) mixing allowing either direct CP violation and/or CP violation in the superpos…

IC‐P‐122: Association of hippocampus head diffusivity and episodic memory performance in early Alzheimer's disease

2009

Measurement of the effective Bs0→K+K− lifetime

2012

A precise determination of the effective $B_s^0 \rightarrow K^+ K^-$ lifetime can be used to constrain contributions from physics beyond the Standard Model in the $B_s^0$ meson system. Conventional approaches select $B$ meson decay products that are significantly displaced from the $B$ meson production vertex. As a consequence, $B$ mesons with low decay times are suppressed, introducing a bias to the decay time spectrum which must be corrected. This analysis uses a technique that explicitly avoids a lifetime bias by using a neural network based trigger and event selection. Using 1.0 fb$^{-1}$ of data recorded by the LHCb experiment, the effective $B_s^0 \rightarrow K^+ K^-$ lifetime is meas…