0000000001177485

AUTHOR

Kirsty J. Elliott-sale

0000-0003-1122-5099

showing 2 related works from this author

A collagen extraction and deuterium oxide stable isotope tracer method for the quantification of bone collagen synthesis rates in vivo.

2021

Abstract The development of safe and practical strategies to prevent weakening of bone tissue is vital, yet attempts to achieve this have been hindered by a lack of understanding of the short‐term (days‐weeks) physiology of bone collagen turnover. To address this, we have developed a method to quantify bone collagen synthesis in vivo, using deuterium oxide (D2O) tracer incorporation techniques combined with gas chromatography pyrolysis isotope‐ratio mass spectrometry (GC‐pyrolysis‐IRMS). Forty‐six male and female rats from a selectively bred model ingested D2O for 3 weeks. Femur diaphyses (FEM), tibia proximal (T‐PRO), and distal (T‐DIS) epiphyses‐metaphyses and tibia mid‐shaft diaphyses (T…

Malemedicine.medical_specialtybone turnoverPhysiologyluukollageenitstable isotopesbiomarkkeritRadiation-Protective Agents030204 cardiovascular system & hematologydeuterium oxideBone tissueGas Chromatography-Mass SpectrometryGC‐pyrolysis‐IRMSBone remodeling03 medical and health sciences0302 clinical medicineIn vivoPhysiology (medical)Internal medicineregeneraatio (biologia)medicineQP1-981AnimalsFemurTibiaFemurcollagen synthesisTibiaChemistryStable isotope ratioExtraction (chemistry)Original ArticlesRatsmedicine.anatomical_structureEndocrinologyDeuteriumGC-pyrolysis-IRMSisotooppianalyysiFemaleOriginal ArticleBone RemodelingCollagenluukudokset030217 neurology & neurosurgeryPyrolysisPhysiological reports
researchProduct

Methodological considerations for studies in sport and exercise science with women as participants: a working guide for standards of practice for res…

2021

AbstractUntil recently, there has been less demand for and interest in female-specific sport and exercise science data. As a result, the vast majority of high-quality sport and exercise science data have been derived from studies with men as participants, which reduces the application of these data due to the known physiological differences between the sexes, specifically with regard to reproductive endocrinology. Furthermore, a shortage of specialist knowledge on female physiology in the sport science community, coupled with a reluctance to effectively adapt experimental designs to incorporate female-specific considerations, such as the menstrual cycle, hormonal contraceptive use, pregnanc…

Malemedicine.medical_specialtynaisetSports medicinefysiologiamedia_common.quotation_subjectSports scienceApplied psychologysukupuolierotReproductive EndocrinologyMEDLINEPhysical Therapy Sports Therapy and RehabilitationkoehenkilötTerminologysukupuolihormonaaliset tekijät03 medical and health sciences0302 clinical medicinemedicineHumansOrthopedics and Sports MedicineExerciseMenstrual Cyclemedia_common030219 obstetrics & reproductive medicinebiologyAthletesmetodologiaexercise science030229 sport sciencesbiology.organism_classificationtutkimuskohteetAdaptation PhysiologicalAthletesCurrent OpinionliikuntatiedeFemalewomenPsychologyInclusion (education)Diversity (politics)Sportsstudies in sport
researchProduct