On the 1-handles of the product V3XBn for a simply connected open 3-manifold V3
Although \pi_1^\inftyV^3 is an obstruction for killing stably the 1-handles of an open simply connected 3-manifold V^3, one can always get rid of the 1-handles of V^3\times B^n, for high enough n, at price of a certain nonmetrizable slackening of the topology.