0000000001188778

AUTHOR

Miomir Jovic

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Anesthetics and Cerebral Protection in Patients Undergoing Carotid Endarterectomy

2015

EREBRAL ISCHEMIA/HYPOXIA may occur in a vari-ety of perioperative circumstances. The main pathophy-siologic aspects involved in cerebral ischemia/reperfusion arecaused by adenosine triphosphate (ATP) consumption, theexcitotoxic actions of glutamate, changes in ionic homeostasis,and formation of free radicals (Fig 1). Outcomes from suchevents range from subclinical neurocognitive deficits to cata-strophic neurologic morbidity or death.

medicine.medical_specialtymedicine.medical_treatmentIschemiaCarotid endarterectomyAnesthesia GeneralNeuroprotectionSevofluraneBrain Ischemia03 medical and health sciences0302 clinical medicine030202 anesthesiologyInternal medicinemedicineAnimalsHumansIschemic PreconditioningSubclinical infectionEndarterectomy Carotidbusiness.industryGlutamate receptorPerioperativeHypoxia (medical)medicine.disease3. Good healthNeuroprotective AgentsAnesthesiology and Pain MedicineAnesthesiaAnesthetics InhalationCardiologymedicine.symptomCardiology and Cardiovascular Medicinebusiness030217 neurology & neurosurgerymedicine.drugJournal of Cardiothoracic and Vascular Anesthesia
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