DOCTORAL: THE FREE APP FOR TUTORING IN SUPPORTIVE ORAL CARE

To introduce the version 2.0 of DoctOral free app, created for tutoring medical/dental professionals (and students) in the clinical recognition of oral lesions and dental treatment planning in patients at risk of ONJ drug- related.

POSSIBLE ROLE OF CRY1 AND CRY2 IN ORAL CARCINOGENESIS

Aim. Dysfunction of the circadian clock is involved in tumorigenesis, and altered expression of some clock genes has been found in cancer patients. It has been shown recently that the occurrence, development, prognosis, and treatment of cancer are closely related to the abnormal expression of certain circadian-clock genes. CRY1 and CRY2 circadian-clock gene plays an important role in the regulation of many normal hysiological rhythms. This proteins act as light-independent inhibitors of CLOCK-BMAL1 components of the circadian clock. It has been revealed recently that abnormal expression of CRY1 and CRY2 correlate closely with the occurrence and development of many cancers. However, the expr…

Oral squamous cell carcinoma as a complication of chronic graft-versus-host disease: a case report

Objectives. Chronic Graft-Versus-Host Disease (cGVHD) is an immunoregulatory disorder which occurs after allogeneic hematopoietic-cell transplantation (HCT) and often shares features of autoimmunity and immunodeficiency. GVHD related oral manifestations include severe oral pain, xerostemia, ulcerative lesions, and mucositis. Furthermore,a major late suggested complication of HSCT is the dramatically increased risk of secondary malignancies including oral cancer and oral cGVHD-releted inflammation may be considered a potential risk factor. Case report. A 51-year-old male patient referred in 1994 to our surgery for cGVHD oral lesions secondary to HCT for acute myelogenous leukemia developed i…

The importance of prevention in the diagnosis and treatment of oral cancer

Healing evaluation by means of Optical Coherence Tomography of an extraction socket with L-PRF application in a patient at ONJ risk: a case report

Early detection of amyloid light-chain amyloidosis: a case report of oral primary manifestation

Oral health assessment in palliate patients: an exploratory preliminary survey

Interventions for treating osteonecrosis of the jaw stage III: may conservative surgical management be a viable option?

Dual localization of oral Kaposi’s sarcoma in HIV-negative patient: a rare case report

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Segmental resection for the excision of two multicystic ameloblastoma

Objectives. The purpose of this study was addressed at the understanding and management in the ameloblastoma treatment, performing a segmental surgical resection. Ameloblastoma represents nearly 1% of all neoplasm located  Annali di Stomatologia 2014; Suppl. 3 to n. 2: 1-41 15 in the oral cavity. In 80% of cases it could be found in the mandible, of these lesions 70% are located in the molar re- gion or the ascending ramus, 20% in the premolar region and 10% in the anterior part. It is considered as a benign neoplasm with slow growing-pattern and locally aggressive behaviour. Methods. On the basis of clinicoradiological findings, ameloblastoma is divided into 3 groups: solid or multicyst…

Concept therapy: Interdisciplinary tumor board for the diagnosis and treatments of head and neck cancer

Occurrence of oro-facial malformations in a tertiary center hospital of Southern Italy: retrospective study on ten thousand newborns

Congenital anomalies (CA) are one of the major cause of infant mortality and childhood morbitity, affecting 2-3% of all babies. Approximately 1% of these newborns have syndromes or multiple anomalies; Cranio-facial anomalies are often a component part of these pathologies. Several newborns with cranio-facial anomalies are affected by syndromes composed of multiple malformations thought to be etiologically and/ or pathogenetically related. One of the most frequent sign of these syndromes is the cleft lip and/or cleft palate. It is estimated that 30% of cleft cases are syndromic and conversely, therefore, approximately 70% are non-syndromic. Oral clefts are among the most widely known and com…

Oro-genital lichen planus in a child: a case report