SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

Results of prototype studies for a spaghetti calorimeter

In the framework of the LAA project, prototypes for a new type of calorimeter, intended for the detection of both electromagnetic (e.m.) and hadronic showers, muons and missing energy (e.g. neutrinos) at high-luminosity multi-TeV pp colliders, were tested. The detector consists of scintillating plastic fibres embedded in a lead matrix at a volume ratio 1:4, such as to achieve compensation. The optimization of the construction of the detector modules is described, as well as the performance concerning e.m. shower and muon detection and e/π separation. We used electron, pion and muon beams in the energy range 10–150 GeV for this purpose. For the energy resolution of electrons we found 13%/trE…

Advances in Technology for High-Energy Subnuclear Physics. Contribution of the LAA Project.

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those…

Clasificación de usos del suelo a partir de imágenes Sentinel-2

[EN] Sentinel-2 (S2), a new ESA satellite for Earth observation, accounts with 13 bands which provide high-quality radiometric images with an excellent spatial resolution (10 and 20 m) ideal for classification purposes. In this paper, two objectives have been addressed: to determine the best classification method for S2, and to quantify its improve-ment with respect to the SPOT operational mission. To do so, four classifiers (LDA, RF, Decision Trees, K-NN) have been selected and applied to two different agricultural areas located in Valencia (Spain) and Buenos Aires (Argentina). All classifiers were tested using, on the one hand, all the S2 bands and, on the other hand, only selecting those…

Electron-pion discrimination with a scintillating fiber calorimeter

Abstract We report on an experimental study of a variety of techniques for discriminating between (isolated) electrons and pions in a lead and scintillating fiber calorimeter without longitudinal segmentation. Using information from the lateral shower development, from a pre-shower detector, from the time structure of the signals, or from a combination of these we measure pion rejection factors of up to several thousand while maintaining electron efficiencies of 95% or higher.

Assessment of the worldwide burden of critical illness: The Intensive Care Over Nations (ICON) audit

Item does not contain fulltext BACKGROUND: Global epidemiological data regarding outcomes for patients in intensive care units (ICUs) are scarce, but are important in understanding the worldwide burden of critical illness. We, therefore, did an international audit of ICU patients worldwide and assessed variations between hospitals and countries in terms of ICU mortality. METHODS: 730 participating centres in 84 countries prospectively collected data on all adult (>16 years) patients admitted to their ICU between May 8 and May 18, 2012, except those admitted for fewer than 24 h for routine postoperative monitoring. Participation was voluntary. Data were collected daily for a maximum of 28 da…