0000000001206866

AUTHOR

A. Ball

showing 5 related works from this author

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Evaluation of appendicitis risk prediction models in adults with suspected appendicitis.

2019

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (pro…

AdulthumanosDecision MakingRisk AssessmentNOapendicectomíaapendicitisevaluación de riesgosAppendectomyHumanshospitalGeneralcollaborativeLS7_4right iliac fossa; appendicitis; collaborativeemergency serviceOriginal Articlesadultoright iliac fossaAppendicitisadult; appendectomy; appendicitis; humans; risk assessment; decision making; emergency service; hospitalLower GIOriginal Articleappendicitis prediction models right iliac fossa painEmergency Service Hospitaltoma de decisiónThe British journal of surgery
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ALEPH: a Detector for Electron-Positron Annihilations at LEP

1990

Process-centred Software Engineering Environments (PSEE) are the most recent generation of environments supporting software development activities. Most of PSEE are based on mechanisms promoting enforcement and automation of process activities. In this kind of mechanisms the process models are prescribed in a detailed and complete way. But the experience shows that supporting processes is more concerned with the flexibility of guidance offered during the process performance than with enforcement of a collection of predefined process models. In this paper, we present a solution to support strategic processes in a PSEE by providing a flexible guidance during process enactment.

PhysicsFlexibility (engineering)Nuclear and High Energy PhysicsAlephhigh-energy physicsProcess modelingProcess (engineering)business.industrySoftware developmentLEPAutomationparticle detectorsData acquisitionDetectors and Experimental TechniquesLEP; particle detectors; high-energy physicsSoftware engineeringbusinessEnforcementInstrumentationparticle detector
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Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

2018

Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those…

MaleOriginalEpidemiology[SDV]Life Sciences [q-bio]HSJ UCIlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]MULTICENTERclinical outcomemortality rateCritical Care and Intensive Care Medicineintensive care unitlaw.invention0302 clinical medicineSeverity of diseaselawEpidemiologymiddle agedMedicine and Health SciencesFAILURE030212 general & internal medicineHospital Mortalityintensive care units -- analysis -- epidemiology -- mortalityGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)CODEScomparative studyintensive careMedicine(all)multilevel analysiIncidenceadultSciences bio-médicales et agricolesIntensive care unit3. Good healthEuropesepsaIntensive Care UnitsfemaleCohortenote intenzivne terapije -- analiza -- epidemiologija -- umrljivostHumanAdultmedicine.medical_specialtyseverity of diseaseCritical CareSepsiIntensive Care UnitUNITED-STATES610 Medicine & healthINTENSIVE-CAREEuropeanArticleSepsisEpidemiology; Sepsis; Severity of disease03 medical and health sciencesAll institutes and research themes of the Radboud University Medical Centerlength of staymaleEpidemiology; Sepsis; Severity of disease; Adult; Europe; Hospital Mortality; Humans; Length of Stay; Male; Critical Care; Intensive Care Units; SepsisAnesthesiologyIntensive careSepsisSCOREmedicineudc:614.2Humanshumanoutcome assessmentSeptic shockbusiness.industrySEPTIC SHOCK030208 emergency & critical care medicineLength of Staymedicine.diseaseTRENDSmajor clinical studySEVERE SEPSIScomorbidity assessmentEmergency medicineEpidemiology; Sepsis; Severity of disease; Critical Care and Intensive Care MedicineObservational studyCLAIMSbusinessSepsis;Severity of disease;Epidemiologyresnost bolezni
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Assessment of the worldwide burden of critical illness: The Intensive Care Over Nations (ICON) audit

2014

Item does not contain fulltext BACKGROUND: Global epidemiological data regarding outcomes for patients in intensive care units (ICUs) are scarce, but are important in understanding the worldwide burden of critical illness. We, therefore, did an international audit of ICU patients worldwide and assessed variations between hospitals and countries in terms of ICU mortality. METHODS: 730 participating centres in 84 countries prospectively collected data on all adult (>16 years) patients admitted to their ICU between May 8 and May 18, 2012, except those admitted for fewer than 24 h for routine postoperative monitoring. Participation was voluntary. Data were collected daily for a maximum of 28 da…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyCritical Illnesshealth care facilities manpower and servicesPopulationlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Critical care european intensive care icon studyComorbidityintensive care medicineGlobal HealthMOF; sepsis; critically ill[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractICON Intensive CareArticleSepsisCohort StudiesOutcome Assessment (Health Care)Intensive careSepsisOutcome Assessment Health CareEpidemiologyHealth careSettore MED/41 - ANESTESIOLOGIAmedicineGlobal healthcritical illness mortalityHumansHospital MortalityeducationIntensive care medicineeducation.field_of_studyMedical Auditbusiness.industryIntensive Caremedicine.diseaseComorbidity3. Good healthIntensive Care UnitsICONbusinessCohort study
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