0000000001212445
AUTHOR
T. Russo
Phenotypic APC resistance as a marker of hypercoagulability in primitive cerebral lymphoma
Thrombosis is the most frequent complication and the second cause of death in patients with malignant disease. Primary central nervous system non-Hodgkin's lymphoma represents a rare pathology. Resistance to APC is usually linked to a factor V (FV) gene mutation changing an Arg 506 to a Gln in the APC cleavage site.In our study, we aimed at investigating the presence of activated protein C resistance (APC-r) and other markers of hypercoagulability in 25 selected patients with a diagnosis of primitive cerebral lymphoma who had suffered from an ischemic episode of TIA and/or stroke.25 selected patients with a diagnosis of primitive cerebral lymphoma and 50 healthy subjects acted as control gr…
Development, human impact and habitat distribution in submarine canyons of the Central and Western Mediterranean
We present in this paper different studies on canyon systems, adopting distinct approaches, temporal and spatial scales. Most of our study areas coincide with the NW Sicilian canyons, which present striking differences in their morphologies in response to the Plio-Quaternary tectonic evolution of the northern Sicilian margin. In the present-day, active sedimentary processes inferred from bedform analyses along some of the studied canyons could drive to enhanced biological activities along them. This is also confirmed by an on-going study of the impact of trawling fishery on the morphology and sedimentary environments of the Sicilian margin, where intense deep-sea bottom trawling activities …