0000000001239153

AUTHOR

C. D. Nunzio

showing 2 related works from this author

Time to recurrence is a significant predictor of cancer-specific survival after recurrence in patients with recurrent renal cell carcinoma - Results …

2013

Objectives To assess the prognostic impact of time to recurrence (TTR) on cancer-specific survival (CSS) after recurrence in patients with renal cell carcinoma (RCC) undergoing radical nephrectomy or nephron-sparing surgery. To analyse differences in clinical and histopathological criteria between patients with early and late recurrence. Patients and Methods Of 13 107 patients with RCC from an international multicentre database, 1712 patients developed recurrence in the follow-up (FU), at a median (interquartile range) of 50.1 (25-106) months. In all, 1402 patients had recurrence at ≤5 years (Group A) and 310 patients beyond this time (Group B). Differences in clinical and histopathological…

Malerenal cell carcinomaTime FactorsTime FactorDatabases FactualPrognosiUrologyprognostic parameterearly recurrencetime to recurrencecancer-specific survivalRetrospective Studielate recurrencenephrectomyHumanscancer survivalCarcinoma Renal Cellrenal cell carcinoma (RCC); time to recurrence; early recurrence; late recurrence; prognostic parameters; cancer-specific survival; nephrectomyAgedRetrospective StudiesKidney NeoplasmMiddle Agedprognostic parametersPrognosisKidney NeoplasmsSurvival Ratecancer survival; early recurrence; late recurrence; nephrectomy; prognostic parameters; renal cell carcinomacancer-specific survival; early recurrence; late recurrence; nephrectomy; prognostic parameters; renal cell carcinoma; time to recurrenceFemaleNeoplasm Recurrence Localrenal cell carcinoma (rcc)cancer-specific survival; early recurrence; late recurrence; nephrectomy; prognostic parameters; renal cell carcinoma (rcc); time to recurrenceHuman
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External Validation of Nomogram Predicting the Probability of Specimen-Confined Disease (pT2-3a, R0N0) in Patients Undergoing Radical Prostatectomy a…

2014

Introduction: Before radical prostatectomy (RP), a nomogram [Briganti et al., Eur Urol 2012;61:584-592] permits to measure the probability of specimen-confined (SC) disease (pT2-pT3a, node negative with negative margins) in high-risk prostate cancer (PCa). The aim of our study was to perform an external validation of this nomogram. Materials and Methods: Between 2007 and 2011, 623 patients with high-risk PCa (prostate-specific antigen (PSA) >20 ng/ml and/or biopsy Gleason score ≥8 and/or clinical stage T3) underwent RP and pelvic lymph node dissection at tertiary referral centers. Multivariable logistic regression models predicting the presence of SC disease were built in; we then used the …

AdultMaleHigh-risk prostate cancermedicine.medical_specialtyUrologymedicine.medical_treatmentHigh-risk prostate cancer; Nomogram; Radical prostatectomyUrologyReproducibility of ResultRadical prostatectomy; High-risk prostate cancer; Nomogramurologic and male genital diseasesSensitivity and SpecificityRegression AnalysiNomogramCohort StudiesRisk FactorsmedicineHumansIn patientMultivariate AnalysiLymph nodeAgedProbabilityAged 80 and overProstatectomyProstatectomybusiness.industryRisk FactorExternal validationProstatic NeoplasmsReproducibility of ResultsMiddle AgedProstate-Specific AntigenNomogramRadical prostatectomyNomogramsProstate-specific antigenDissectionmedicine.anatomical_structureROC CurveProstatic NeoplasmCalibrationMultivariate AnalysisLymph Node ExcisionRegression AnalysisCohort StudiebusinessHuman
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