0000000001242273

AUTHOR

I. Esteban

showing 1 related works from this author

p75NTRin the spleen: Age-dependent changes, effect of NGF and 4-methylcatechol treatment, and structural changes in p75NTR-deficient mice

2003

In addition to their well-known actions within the nervous system, neurotrophins and their receptors are involved in immune system functioning, as demonstrated by their wide distribution in lymphoid tissues and their in vitro actions on immunocompetent cells. Nevertheless, the in vivo roles of neurotrophin-receptor systems in lymphoid tissues, as well as the scope of their influence throughout development and adulthood, are yet to be clarified. In the present study, we used combined morphological and immunohistochemical techniques to investigate the presence and cellular localization of p75NTR, the pan-neurotrophin receptor protein, in rat spleen from newborns to aging individuals, and the …

Nervous systemWhite pulpmedicine.medical_specialtyPathologybiologySpleenAgricultural and Biological Sciences (miscellaneous)medicine.anatomical_structureImmune systemNerve growth factorEndocrinologyInternal medicinemedicinebiology.proteinsense organsAnatomyReceptorCellular localizationNeurotrophinThe Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology
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