0000000001247580

AUTHOR

Marcella Nebbioso

showing 4 related works from this author

High myopic patients with and without foveoschisis: morphological and functional characteristics.

2020

Purpose: Myopic foveoschisis (MF) is characterized by the splitting of the retinal layers in the fovea of patients with high myopia (HM). MF may progress into foveal detachment or macular hole formation with consequent loss of central vision. The aim of this study is to investigate morphological and functional changes of the macular region in myopic subjects with and without foveoschisis. Design: Observational, cross-sectional, comparative study. Methods: Forty-eight patients with HM and 24 healthy controls were evaluated by spectral domain-optical coherence tomography (SD-OCT), multifocal electroretinography (mfERG) and microperimetry (MP-1) tests to assess macular thickness, functionality…

Myopic foveoschisisMalemedicine.medical_specialtyFovea Centralisgenetic structuresRetinoschisisVisual AcuityRetinoschisisFoveoschisisRetina03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePhysiology (medical)OphthalmologyHigh myopiaVitrectomyPost-hoc analysismedicineChi-square testElectroretinographyHumansMacular holePathological myopiabusiness.industryMultifocal electroretinography (mfERG)RetinalMiddle Agedmedicine.diseaseRetinal Perforationseye diseasesSensory SystemsSpectral domain-optical coherence tomography (SD-OCT)high myopia; microperimetry (MP-1); multifocal electroretinography (mfERG); myopic foveoschisis; pathological myopia; retinoschisis; spectral domain-optical coherence tomography (SD-OCT)OphthalmologyCross-Sectional StudieschemistryMyopia Degenerative030221 ophthalmology & optometryMicroperimetry (MP-1)Visual Field TestsFemalesense organsAnalysis of varianceVisual FieldsbusinessMicroperimetry030217 neurology & neurosurgeryTomography Optical CoherenceDocumenta ophthalmologica. Advances in ophthalmology
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Recent advances and disputes about curcumin in retinal diseases

2021

Abstract Curcumin belongs to the group of so-called phytocompounds, biologically active molecules produced by plants exerting a beneficial effect on health. Curcumin shows a wide spectrum of different properties, being an anti-inflammatory, antioxidant, antimicrobial and antimutagenic molecule. The purpose of the review is to examine what literature reported on the characteristics of curcumin, particularly, on the beneficial and controversial aspects of this molecule, aiming for a better therapeutic management of retinal diseases. The retina is a constant target of oxidative stress, this tissue being characterized by cells rich in mitochondria and by vessels and being, obviously, continuous…

medicine.medical_specialtyProliferative vitreoretinopathyantioxidant proprietiesReviewexosomesPharmacologymedicine.disease_causeRetinal ganglionanti-inflammatory proprieties; antioxidant proprieties; exosomes; miRNA; nanosphere; natural compounds03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOphthalmologymedicinenatural compoundsanti-inflammatory proprietiesmiRNARetinabusiness.industryRetinalDiabetic retinopathyMacular degenerationmedicine.diseasenanosphereOphthalmologymedicine.anatomical_structurechemistry030221 ophthalmology & optometryCurcuminbusiness030217 neurology & neurosurgeryOxidative stress
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Optical coherence tomography angiography evaluation of peripapillary microvascular changes after rhegmatogenous retinal detachment repair

2021

PURPOSE To evaluate the radial peripapillary capillary plexus (RPCP) vessel density (VD) and the retinal nerve fiber layer (RNFL) thickness in eyes successfully treated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. METHODS In this cross-sectional multicenter clinical study, eyes with a minimum 12-month follow-up were reexamined. The RPCP VD and RNFL thickness in the rhegmatogenous retinal detachment subfields of the affected eye (study group) were compared with the corresponding areas of the healthy fellow eyes (control group). RESULTS Fifty-three eyes were included in the study. A significantly lower RPCP VD and RNFL thickness were observed in those subfields af…

MaleRetinal Ganglion Cellsgenetic structuresComputed Tomography Angiographymedicine.medical_treatmentNerve fiber layerVisual AcuityVitrectomyEyeradial peripapillary capillary plexuschemistry.chemical_compoundNerve FibersVitrectomyTomographyRetinal detachment repairRetinal detachmentGeneral MedicineMiddle AgedAxial Length Eyemedicine.anatomical_structureFemaleTomography Optical CoherencePars planamedicine.medical_specialtyBiometryOptic DiskEndotamponaderetinal detachmentOCT-angiography; Radial peripapillary capillary plexus; Retinal detachment; Retinal nerve fiber layer; Aged; Axial Length Eye; Biometry; Cross-Sectional Studies; Endotamponade; Female; Humans; Male; Middle Aged; Nerve Fibers; Optic Disk; Retinal Detachment; Retinal Ganglion Cells; Retinal Vessels; Retrospective Studies; Visual Acuity; Computed Tomography Angiography; Tomography Optical Coherence; VitrectomyOphthalmologymedicineHumansAxial LengthAgedRetrospective StudiesRetinabusiness.industryradial peripapillary capillary plexus; OCT-angiography; retinal nerve fiber layer; retinal detachmentRetinal Vesselsretinal nerve fiber layerRetinalOptical coherence tomography angiographymedicine.diseaseeye diseasesOphthalmologyCross-Sectional StudieschemistryOptical Coherencesense organsOCT-angiographybusiness
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OCT-Angiography evaluation of peripapillary microvascular changes after rhegmatogenous retinal detachment repair

2021

Purpose: To evaluate the radial peripapillary capillary plexus (RPCP) vessel density (VD) and the retinal nerve fiber layer (RNFL) thickness in eyes successfully treated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. Methods: In this cross-sectional multicenter clinical study, eyes with a minimum 12-month follow-up were reexamined. The RPCP VD and RNFL thickness in the rhegmatogenous retinal detachment subfields of the affected eye (study group) were compared with the corresponding areas of the healthy fellow eyes (control group). Results: Fifty-three eyes were included in the study. A significantly lower RPCP VD and RNFL thickness were observed in those subfields…

Retinal nerve fiber layerRadial peripapillary capillary plexusOCT-Angiography
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