0000000001251631

AUTHOR

G. Zaccai

showing 1 related works from this author

The effect of water on protein dynamics

2004

Neutron diffraction and spectroscopy were applied to describe the hydration and dynamics of a soluble protein and a natural membrane from extreme halophilic Archaea. The quantitative dependence of protein motions on water activity was clearly illustrated, and it was established that a minimum hydration shell is required for the systems to access their functional resilience, i.e. a dynamics state that allows biological activity.

Dynamical transitionWater activityNeutron diffractionHalophilic malate dehydrogenaseBacteriorhodopsinHydration shellNeutronEuryarchaeotaGeneral Biochemistry Genetics and Molecular BiologyMalate DehydrogenaseSpectroscopySpectrum AnalysibiologyChemistrySpectrum AnalysisProtein dynamicsWaterBacteriorhodopsinPurple membraneAgricultural and Biological Sciences (miscellaneous)Settore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Neutron DiffractionMembraneSolvation shellAgricultural and Biological Sciences (all)BiochemistryChemical physicsBacteriorhodopsinsbiology.proteinBacteriorhodopsinsGeneral Agricultural and Biological SciencesResearch ArticlePhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences
researchProduct