0000000001253113
AUTHOR
M. Simoncini
Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes
Background Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage ≥3 CKD in a large cohort of patients affected by T1DM. Methods A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici D…
Experimental and numerical analysis on FSWed magnesium alloy thin sheets obtained using “pin” and “pinless” tool
Experimental and numerical analysis on post welding formability of FSWed AZ31 magnesium alloy thin joints obtained using a "Pinless" tool configuration
The post welding formability of friction stir welded AZ31 magnesium alloy thin sheets (1.5 mm thick), obtained using a “pinless” tool configuration, was widely investigated by means of the hemispherical punch method at 350°C, with a constant crosshead speed of 0.1 mm/s. The results were compared with those obtained on the base material. It has shown that formability of the joints is lower than the one of the base material. The experimental work was supported by a numerical investigation based on FEM in order to highlight the material flow occurring during the welding process. Additionally, hemispherical punch tests were simulated starting from the calculated conditions, in terms of accumula…
Thermo-mechanical testing of Li-ceramic for the helium cooled pebble bed (HCPB) breeding blanket
The helium cooled pebble bed (HCPB) Test blanket module (TBM) for the DEMO Reactor foresees the utilization of lithiate ceramics as breeder in form of pebble beds. The pebbles are organized in several layers alternatively stacked among couples of cooling plates (CP). ENEA has launched an experimental programme for the out-of-pile thermo-mechanical testing of mock-ups simulating a portion of the HCPB-TBM. The programme foresees the fabrication and testing of different mock-ups, to be tested in the HE-FUS3 facility at ENEA Brasimone. The paper describes the HELICHETTA III campaign carried-out in 2003. In particular, the test section layout, the pebble filling procedure, the experimental set-u…
Experimental tests on Li-ceramic breeders for the helium cooled pebble bed (HCPB) blanket design
The Helium Cooled Pebble Bed (HCPB) Test Blanket Module (TBM) to be tested in ITER (International Thermonuclear Experimental Reactor) Reactor foresees the utilization of Lithiate ceramics as Tritium breeder in form of pebble beds. Since 1998, ENEA has launched many experimental activities for the evaluation of the breeder thermomechanics and the interaction between the pebble beds and the prismatic steel containment walls. Main objectives of these activities are the measurement of the pebble bed effective thermal conductivity, the wall heat transfer coefficient, the pressure loads and deformations on the lateral walls and their dependency from the mechanical constraints. The paper presents …