Author: J. Esplunges

0000000001258823

AUTHOR

J. Esplunges

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Analgesic and central depressor effects of the dichloromethanol extract fromSchinus molle L.

1997

The analgesic and central depressor effects of the dichloromethanol extract of Schinus molle L. were analysed in in vivo models. This extract showed low acute toxicity, CNS depressor activity and analgesic effect. Following further fractionation, the hexane/dichloromethane (75/25) fraction showed the most interesting results. Thus, this fraction caused a total inhibition of motor activity and significantly reduced the threshold of pain to chemical stimulus. © 1997 John Wiley & Sons, Ltd.

PharmacologySchinus mollebiologyTraditional medicineIn vivoChemistryThreshold of painAnalgesicToxicityBiological activityPharmacognosybiology.organism_classificationAcute toxicityPhytotherapy Research

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