Analgesic and central depressor effects of the dichloromethanol extract fromSchinus molle L.

6533b871fe1ef96bd12d1837

RESEARCH PRODUCT

Analgesic and central depressor effects of the dichloromethanol extract fromSchinus molle L.

M D Barrachina R. Bello Eduardo Primo-yúfera J. Esplunges M. A. Martínez-cuesta

subject

Pharmacology Schinus molle biology Traditional medicine In vivo Chemistry Threshold of pain Analgesic Toxicity Biological activity Pharmacognosy biology.organism_classification Acute toxicity

description

The analgesic and central depressor effects of the dichloromethanol extract of Schinus molle L. were analysed in in vivo models. This extract showed low acute toxicity, CNS depressor activity and analgesic effect. Following further fractionation, the hexane/dichloromethane (75/25) fraction showed the most interesting results. Thus, this fraction caused a total inhibition of motor activity and significantly reduced the threshold of pain to chemical stimulus. © 1997 John Wiley & Sons, Ltd.

year	journal	country	edition	language
1997-06-01	Phytotherapy Research

https://doi.org/10.1002/(sici)1099-1573(199706)11:4<317::aid-ptr91>3.0.co;2-m

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