Association between increased arterial stiffness and clinical outcomes in patients with early sepsis: a prospective observational cohort study.

Background Conduit arteries, especially the aorta, play a major role in ensuring efficient cardiac function and optimal microvascular flow due to their viscoelastic properties. Studies in animals and on isolated arteries show that acute systemic inflammation can cause aortic stiffening which affects hemodynamic efficiency. Carotid-femoral pulse wave velocity, a measure of aortic stiffness, may be useful as a bedside investigational method in patients with early sepsis admitted to intensive care, as circulatory changes can lead to multiple organ failure and increased mortality. This study aims to investigate arterial stiffness in early sepsis and its association with clinical outcomes. Metho…

Additional file 1: of Association between increased arterial stiffness and clinical outcomes in patients with early sepsis: a prospective observational cohort study

Table S1. Results of Cox regression analysis of the association between pulse wave velocity and length of survival. (DOCX 15 kb)

David V procedure with concomitant ascending aorta, aortic arch and descending aorta replacement in adult patient with coarctation of aorta

Additional file 1: of Association between increased arterial stiffness and clinical outcomes in patients with early sepsis: a prospective observational cohort study

Table S1. Results of Cox regression analysis of the association between pulse wave velocity and length of survival. (DOCX 15 kb)