0000000001268755
AUTHOR
F. Ahmed
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…
Cluster visual field progression and its relationship with optic disc changes
Purpose Glaucoma diagnosis and follow up of progression is often based on structural and functional assessments. This study aimed to assess clustered progression and evaluate its correlation with the corresponding disc changes (RA sectors) obtained from HRT examinations. Methods 51 eyes from OHT and glaucoma patients with a minimum of 5 reliable visual ᴀ밄eld tests (HFA II i 24-2) and HRT with a follow-up >4 years were analyzed retrospectively. Linear regression of clusters deᴀ밄ned by the Glaucoma Hemiᴀ밄eld Test (GHT) was performed based on the mean threshold in each cluster. Global and sectoral rates of change in RAs were assessed and correlated with functional clustered measures. Cluste…