A brain inspired architecture for an outdoor robot guide

HSP60 is muscle fiber-type specific and increases after endurance training: Mice model

Heat shock protein (Hsp) 60 plays a key role in the translocation of proteins and cytoprotection, is primarily localized inside mitochondrial, and its levels increase in skeletal muscle upon exercise (Folkesson et al., 2013). The aim of this study was to examine muscle fiber specificity of HSP60 at rest and after an endurance training program of 45 days. Forth-eight male young (7-weeks old) healthy mice (BALB/c) were subdivided into six groups (8 mice per group). Three groups were trained on a rota-rod, at a gradually increasing duration and speed; while the other three groups did not perform any type of regular physical activity. One group of each condition was sacrificed after 15, 30 and …

Comparative analysis of the structure of temporomandibular joint in human and rabbit.

In order to increase knowledge on the morphology and structure of the articular disc of the temporomandibular joint (TMJ) for a better understanding of the functional role of the same, it proceeded with an investigation on histological samples in the block of TMJ and periarticular tissues of adult rabits and human fatustes at different stage of development. (www.actabiomedica.it)

Hsp60 expression in skeletal muscle increase after endurance training

" Effectiveness of G-CSF+ plerixafor mobilization in B-talassemia patients and whole gene expression analysis of the harvested CD34+ cell"

Rituximab for managing relapsing or refractory patients with idiopathic thrombotic thrombocytopenic purpura – haemolytic uraemic syndrome

Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery.

BACKGROUND: Heat shock protein 60 (Hsp60) is a chaperonin involved in tumorigenesis, but its participation in tumor development and progression is not well understood and its value as a tumor biomarker has not been fully elucidated. In the current study, the authors presented evidence supporting the theory that Hsp60 has potential as a biomarker as well as a therapeutic target in patients with large bowel cancer. METHODS: The authors studied a population of 97 subjects, including patients and controls. Immunomorphology, Western blot analysis, and quantitative real-time polymerase chain reaction were performed on tissue specimens. Exosomes were isolated from blood and characterized by electr…

Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study

The outbreak of severe acute respiratory syndromecoronavirus-2, the cause of coronavirus disease 2019 (COVID-19) in December 2019 represented a global emergency accounting for more than 2.5 million deaths worldwide.1 It has had an unprecedented influence on cardiac surgery internationally, resulting in cautious delivery of surgery and restructuring of services.2 Understanding the influence of COVID-19 on patients after cardiac surgery is based on assumptions from other surgical specialties and single-center studies. The COVIDSurg Collaborative conducted a multicenter cohort study, including 1128 patients, across 235 hospitals, from 24 countries demonstrating perioperative COVID-19 infection…

Standard di servizio per le comunità terapeutiche per l'infanzia e l'adolescenza. Adattamento alla cultura italiana.

Alcohol, Cannabinoids and Nicotine in liver pathophysiology

The liver can be affected by a wide range of therapeutic and environmental chemicals and here we want to provide a summary of the complex effects of alcohol, cannabinoids and nicotine on liver function. Alcohol is the most important agent that produces liver injury, manifesting as alcoholic fatty liver disease. In addition, it is one of the main etiologic agents for hepatocellular carcinoma development. Studies reviewed in this article regarding cannabinoids, show that Δ9-THC does not produce any harmful effects on the liver, while cannabidiol has hepatoprotective effects in ischemia/reperfusion and alcohol-induced liver injuries. The liver is negatively affected by nicotine exposure, but s…

Relapsing or refractory idiopathic thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: the role of rituximab.

Prevalence and correlates of QTc prolongation in Italian psychiatric care: cross-sectional multicentre study.

Aims.In recent years several warnings have been issued by regulatory authorities on the risk of electrocardiogram abnormalities in individuals exposed to psychotropic drugs. As a consequence of these warnings, monitoring of the QT interval corrected for heart rate (QTc) has become increasingly common. This study was conducted to measure the frequency of QTc prolongation in unselected psychiatric patients, and to document the associated factors using a cross-sectional approach.Method.The study was carried out in 35 Italian psychiatric services that are part of the STAR (Servizi Territoriali Associati per la Ricerca) Network, a research group established to produce scientific knowledge by col…

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

The British journal of surgery 108(11), 1274-1292 (2021). doi:10.1093/bjs/znab183

Autophagic flux restoration by exercise or pharmacological treatment counteracts cancer cachexia