0000000001294486
AUTHOR
R. Sola
Undetectable HCV-RNA at treatment-week 8 results in high-sustained virological response in HCV G1 treatment-experienced patients with advanced liver disease: The International Italian/Spanish Boceprevir/Peginterferon/Ribavirin Name Patients Program
In many countries, first-generation protease inhibitors (PIs)/peginterferon/ribavirin (P/R) still represent the only treatment option for HCV-infected patients. Subjects with advanced disease and previous failure to P/R urgently need therapy, but they are under-represented in clinical trials. All treatment-experienced F3/4 Metavir patients who received boceprevir (BOC)+P/R in the Italian-Spanish Name Patient Program have been included in this study. Multivariate logistic regression analysis (MLR) was used to identify baseline and on-treatment predictors of SVR and adverse events (AEs). Four hundred and sixteen patients, mean age 57.7 (range 25-78 years), 70% males, 69.5% (289/416) F4, 14% (…
Una lesión rara: el lipoma intraóseo: Presentación de dos casos
Se presentan 2 casos de lipoma intraóseo, uno de ellos bilateral en ambos calcáneos y el otro localizado en la parte proximal de la tibia derecha de otro paciente. El caso bilateral de calcáneo fue tratado de forma conservadora. El caso localizado en la tibia fue intervenido quirúrgicamente, realizándosele curetaje de la lesión y relleno con injerto de esponjosa antólogo. La evolución fue satisfactoria en los 3 casos, sin dolor ni repercusión funcional en los pacientes. This report presents two cases of intraosseus lipomans one of which were bilateral calcaneus and the other was found in the proximal area of another patient's right tibiae. The first was treated conservatively, whereas surgi…