0000000001295905

AUTHOR

Leticia Odriozola

showing 2 related works from this author

Detection of Missing Proteins Using the PRIDE Database as a Source of Mass Spectrometry Evidence

2016

The current catalogue of the human proteome is not yet complete, as experimental proteomics evidence is still elusive for a group of proteins known as the missing proteins. The Human Proteome Project (HPP) has been successfully using technology and bioinformatic resources to improve the characterization of such challenging proteins. In this manuscript, we propose a pipeline starting with the mining of the PRIDE database to select a group of data sets potentially enriched in missing proteins that are subsequently analyzed for protein identification with a method based on the statistical analysis of proteotypic peptides. Spermatozoa and the HEK293 cell line were found to be a promising source…

0301 basic medicineMaleProteomicsFrontal cortexFuture studiesProteomePlacentaBiologyMass spectrometrycomputer.software_genreTandem mass spectrometryProteomicsBiochemistryArticleRetina03 medical and health sciencesPregnancyTandem Mass SpectrometryMS/MS proteomicsHuman proteome projectHumansDatabases ProteinAortaPRIDE databaseDatabaseC-HPPComputational BiologyGeneral ChemistrySpermatozoaFrontal Lobe030104 developmental biologyHEK293 CellsProteomeProtein identificationFemalemissing proteinscomputerJournal of Proteome Research
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Multi-laboratory experiment PME11 for the standardization of phosphoproteome analysis

2022

6 p.-2 fig.-2 tab.

ProteomicsenrichmentStandardizationProteomeComputer scienceCellbiologiMass-spectrometryBiophysics610 Medicine & healthComputational biologyBioinformatik och systembiologiProteòmicaProteomics:Chemical Phenomena::Biochemical Phenomena::Phosphorylation [PHENOMENA AND PROCESSES]BiochemistryExperimentFosforilació:Natural Science Disciplines::Biological Science Disciplines::Biochemistry::Proteomics [DISCIPLINES AND OCCUPATIONS]:Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Inter-laboratoryPhosphorylationquality controlEpidemiologia610 Medicine & healthBioinformatics and Systems BiologyFosfoproteïnes:fenómenos químicos::fenómenos bioquímicos::fosforilación [FENÓMENOS Y PROCESOS]:disciplinas de las ciencias naturales::disciplinas de las ciencias biológicas::bioquímica::proteómica [DISCIPLINAS Y OCUPACIONES]PhosphoproteomicsBiochemistry and Molecular BiologyReproducibility of ResultsCell BiologyReference Standards:técnicas de investigación::métodos epidemiológicos::diseño de la investigación epidemiológica::reproducibilidad de los resultados [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]NormalitzacióPhosphoproteinsStandardizationReference samplePhosphoproteomeProteomeLaboratory experimentLaboratoriesBiokemi och molekylärbiologi
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