0000000001301855
AUTHOR
Javier Cuenca
Empirical Autotuning of Two-level Parallel Linear Algebra Routines on Large cc-NUMA Systems
In large cc-NUMA systems the efficient use of the different levels of the memory hierarchy is not an easy task, and the performance of multithreading implementations of the libraries decreases when the number of cores used increases, so producing an important lost of efficiency. To alleviate this problem, routines with multilevel parallelism can be developed by combining OpenMP and BLAS parallelism. In that way, higher performance can be achieved, but it is necessary to develop some autotuning technique for the appropriate selection of the number of threads to use at each level. The selection can be made through theoretical models of the execution time or some installation methodology. This…
Expression and purification of polyhistidine-tagged rotavirus NSP4 proteins in insect cells
The rotavirus nonstructural NSP4 protein, a transmembrane endoplasmic reticulum-specific glycoprotein, has been described as the first viral enterotoxin. Purified NSP4 or a peptide corresponding to NSP4 residues 114-135 induces diarrhea in young mice. NSP4 has a membrane-destabilizing activity and causes an increase in intracellular calcium levels and chloride secretion by a calcium-dependent signalling pathway in eucaryotic cells. In this study, four recombinant baculoviruses were generated expressing the rotavirus NSP4 glycoprotein from the human strains Wa and Ito, the porcine strain OSU, and the simian strain SA11, which belong to two different NSP4 genotypes, A and B. The recombinant g…
La Consultoría Política
Duración: 26M
La Cooperación Internacional
Ciencias Políticas y de la AdministraciónDuración: 57M