0000000001306925
AUTHOR
Xin Qiao
G protein-coupled odorant receptors underlie mechanosensitivity in mammalian olfactory sensory neurons
Mechanosensitive cells are essential for organisms to sense the external and internal environments, and a variety of molecules have been implicated as mechanical sensors. Here we report that odorant receptors (ORs), a large family of G protein-coupled receptors, underlie the responses to both chemical and mechanical stimuli in mouse olfactory sensory neurons (OSNs). Genetic ablation of key signaling proteins in odor transduction or disruption of OR–G protein coupling eliminates mechanical responses. Curiously, OSNs expressing different OR types display significantly different responses to mechanical stimuli. Genetic swap of putatively mechanosensitive ORs abolishes or reduces mechanical res…
A new enneanuclear nickel(II) cluster with a rectangular face-centered trigonal prism structure and cluster glass behavior.
An enneanuclear nickel(II) complex with a rectangular face-centered trigonal prism structure bridged by μ(2)-pyrazolate, μ(6)-CO(3)(2-) and μ(3)-OH(-) groups was synthesized. It displays cluster glass-like magnetic behavior assigned to the single molecule magnet properties of {Ni(9)} clusters and weak intercluster interaction.
CCDC 644657: Experimental Crystal Structure Determination
Related Article: Jing-Yuan Xu, Hai-Bin Song, Gong-Feng Xu, Xin Qiao, Shi-Ping Yan, Dai-Zheng Liao, Y.Journaux, J.Cano|2012|Chem.Commun.|48|1015|doi:10.1039/c1cc16243h