Author: M. Baguena

0000000001307877

AUTHOR

M. Baguena

showing 7 related works from this author

Vanillin cell sensor

2007

Our project for iGEM 2006 consisted of designing a cellular vanillin biosensor. We used an EnvZ -E. coli strain as a chassis, and constructed two different devices: a sensor and an actuator, assembled using OmpR-P as a standardised mediator. The sensor device contained a computation- ally designed vanillin receptor and a synthetic two-component signal transduction protein (Trz). The receptor protein was based on a ribose-binding protein as scaffold. The Trz was built by fusion of the periplasmic and transmembrane domains of a Trg protein with an EnvZ kinase domain. When the receptor complex binds Trg, an allosteric motion is propagated to the cyto- plasmic EnvZ kinase domain, resulting in a…

0303 health sciencesReceptor complex030303 biophysicsAllosteric regulationAutophosphorylationBioengineeringCell BiologyBiologyCell biology03 medical and health sciencesSynthetic biologyTransmembrane domainProtein kinase domainBiochemistry[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologySignal transductionMolecular BiologyTranscription factor030304 developmental biologyBiotechnologyIET Synthetic Biology

researchProduct

CCDC 288794: Experimental Crystal Structure Determination

2006

Related Article: M.E.Gonzalez-Nunez, J.Royo, R.Mello, M.Baguena, J.M.Ferrer, C.R.de Arellano, G.Asensio, G.K.S.Prakash|2005|J.Org.Chem.|70|7919|doi:10.1021/jo0509511

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(Z)-2-(5-Hydroxyadamantyl)methylketone

researchProduct

CCDC 288792: Experimental Crystal Structure Determination

2006

Related Article: M.E.Gonzalez-Nunez, J.Royo, R.Mello, M.Baguena, J.M.Ferrer, C.R.de Arellano, G.Asensio, G.K.S.Prakash|2005|J.Org.Chem.|70|7919|doi:10.1021/jo0509511

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(E)-5-Hydroxy-2-adamantyl methylsulfonate

researchProduct

CCDC 288796: Experimental Crystal Structure Determination

2006

Related Article: M.E.Gonzalez-Nunez, J.Royo, R.Mello, M.Baguena, J.M.Ferrer, C.R.de Arellano, G.Asensio, G.K.S.Prakash|2005|J.Org.Chem.|70|7919|doi:10.1021/jo0509511

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(Z)-(5-Hydroxy-2-adamantyl)methylsulfoneExperimental 3D Coordinates

researchProduct

CCDC 288793: Experimental Crystal Structure Determination

2006

Related Article: M.E.Gonzalez-Nunez, J.Royo, R.Mello, M.Baguena, J.M.Ferrer, C.R.de Arellano, G.Asensio, G.K.S.Prakash|2005|J.Org.Chem.|70|7919|doi:10.1021/jo0509511

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(Z)-5-Hydroxy-2-adamantyl methylsulfonate

researchProduct

CCDC 288795: Experimental Crystal Structure Determination

2006

Related Article: M.E.Gonzalez-Nunez, J.Royo, R.Mello, M.Baguena, J.M.Ferrer, C.R.de Arellano, G.Asensio, G.K.S.Prakash|2005|J.Org.Chem.|70|7919|doi:10.1021/jo0509511

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(E)-(5-Hydroxy-2-adamantyl)methylsulfoneExperimental 3D Coordinates

researchProduct

CCDC 288791: Experimental Crystal Structure Determination

2006

Related Article: M.E.Gonzalez-Nunez, J.Royo, R.Mello, M.Baguena, J.M.Ferrer, C.R.de Arellano, G.Asensio, G.K.S.Prakash|2005|J.Org.Chem.|70|7919|doi:10.1021/jo0509511

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(Z)-4-Chloro-1-adamantanolExperimental 3D Coordinates

researchProduct

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