0000000001307966

AUTHOR

B. Grimm

showing 2 related works from this author

Ligase Chain Reaction (LCR®) assay for semi-quantitative detection of HBV DNA in mononuclear leukocytes of patients with chronic hepatitis B

1996

Summary. A ligase chain reaction (LCR®)-based approach to detect hepatitis B virus (HBV) DNA in peripheral blood mononuclear cells (PBMC) is described. Using this new amplification technique, we determined semi-quantitatively the amount of a short HBV S-gene fragment in PBMC lysates of 25 patients with different forms of chronic hepatitis (group A (n= 8), hepatitis B s antigen (HBsAg)+/hepatitis B e antigen (HBeAg)+; group B (n= 9), HBsAg+/HBeAg-; group C (n= 8), HBsAg-/HBeAg-). The LCR results were compared with the findings obtained with polymerase chain reaction (PCR) amplification of three distinct HBV gene regions (preS1/2, S and C) and related to the serological profiles of the patien…

Hepatitis B virusHBsAgHepatitis B virus DNA polymerasemedicine.disease_causePolymerase Chain ReactionSensitivity and Specificitylaw.inventionLigaseslawVirologymedicineHumansHepatitis B e AntigensLigase chain reactionPolymerase chain reactionHepatitis B virusHepatitis B Surface AntigensHepatologyClinical Laboratory Techniquesbusiness.industryvirus diseasesHepatitis BHepatitis Bmedicine.diseaseVirologyMolecular biologydigestive system diseasesInfectious DiseasesHBeAgDNA ViralLeukocytes MononuclearPrimer (molecular biology)business
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CCDC 843819: Experimental Crystal Structure Determination

2012

Related Article: H.Isla, B.Grimm, E.M.Perez, M.R.Torres, M.A.Herranz, R.Viruela, J.Arago, E.Orti, D.M.Guldi, N.Martin|2012|Chemical Science|3|498|doi:10.1039/c1sc00669j

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters1015-bis(13-dithiol-2-ylidene)-1015-dihydro-5H-diindeno[12-a:1'2'-c]fluoren-5-oneExperimental 3D Coordinates
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