0000000001309767

AUTHOR

Jan-hendrik Schöbel

showing 6 related works from this author

Diastereoselective Synthesis of Spiro[pyrazolone-4,3′-tetrahydrothiophenes] via a Sulfa-Michael/Aldol Domino Reaction

2016

Synthesis : journal of synthetic organic chemistry 48(23), 4091-4098(2016). doi:10.1055/s-0035-1562473

Reaction conditions010405 organic chemistryChemistryOrganic ChemistryPyrazolone010402 general chemistry54001 natural sciencesCombinatorial chemistryCatalysisDomino0104 chemical scienceschemistry.chemical_compoundCascade reactionAldol reactionYield (chemistry)ddc:540medicineOrganic chemistryTetrahydrothiophenemedicine.drug
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1,2,6-Thiadiazine 1-Oxides: Unsaturated Three-Dimensional S,N-Heterocycles from Sulfonimidamides.

2020

Unprecedented three-dimensional 1,2,6-thiadiazine 1-oxides have been prepared by an aza-Michael-addition/cyclization/condensation reaction sequence starting from sulfonimidamides and propargyl ketones. The products have been further functionalized by standard cross-coupling reactions, selective bromination of the heterocyclic ring, and conversion into a β-hydroxy substituted derivative. A representative product was characterized by single-crystal X-ray structure analysis. peerReviewed

sulfonimidamidessingle-crystal X-raybioaktiiviset yhdisteet010405 organic chemistryStereochemistryChemistryOrganic ChemistryOxideHalogenation010402 general chemistryCondensation reaction01 natural sciencesBiochemistryCoupling reaction0104 chemical scienceschemistry.chemical_compoundPropargylPhysical and Theoretical ChemistrySequence (medicine)Organic letters
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1,2‐Benzothiazine Derivatives from Sulfonimidamides by Metal‐Catalyzed Annulation Reactions in Solution and under Solvent‐Free Mechanochemical Condit…

2021

Advanced synthesis & catalysis (2021). doi:10.1002/adsc.202001505 special issue: "Hot Topic: C-H Activation"

Annulationkemiallinen synteesiSolvent free660iridium catalysisChemistrysulfonimidamideGeneral ChemistryBenzothiazine12-benzothiazineC−H activationCatalysisMetalchemistry.chemical_compoundMechanochemistryvisual_artkatalyysirikkiyhdisteetddc:660visual_art.visual_art_mediumrhodium catalysisOrganic chemistrymechanochemistryorgaaniset yhdisteet
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Synthesis of trifluoromethyl-substituted 1,2,6-thiadiazine 1-oxides from sulfonimidamides under mechanochemical conditions

2021

TBS-protected or NH-sulfonimidamides react with β-alkoxyvinyl trifluoromethylketones under solvent-free mechanochemical conditions to give 3-trifluoromethyl-substituted three-dimensional 1,2,6-thiadiazine 1-oxides. C4-Functionalized products can be obtained by starting from cyclic enones and brominations of the initially formed heterocycles. The stability of the products was investigated by varying the pH value and storage under aerobic conditions.

chemistry.chemical_compoundTrifluoromethylChemistryOrganic ChemistryOrganic chemistryPhysical and Theoretical ChemistryBiochemistryValue (mathematics)Organic & Biomolecular Chemistry
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CCDC 1985011: Experimental Crystal Structure Determination

2020

Related Article: Jan-Hendrik Schöbel, Marco Thomas Passia, Nadja Anna Wolter, Rakesh Puttreddy, Kari Rissanen, Carsten Bolm|2020|Org.Lett.|22|2702|doi:10.1021/acs.orglett.0c00666

Space GroupCrystallographyCrystal System3-t-butyl-1-(4-methylphenyl)-5-phenyl-12-dihydro-1lambda626-thiadiazin-1-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1484545: Experimental Crystal Structure Determination

2016

Related Article: Ugur Kaya, Suruchi Mahajan, Jan-Hendrik Schöbel, Arto Valkonen, Kari Rissanen and Dieter Enders|2016|Synthesis|48|4091|doi:10.1055/s-0035-1562473

6-(3-chlorophenyl)-1-methyl-4-oxo-3-phenyl-7-thia-23-diazaspiro[4.4]non-1-en-9-yl acetateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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