0000000001310690

AUTHOR

ÁLvaro Somoza

showing 5 related works from this author

Rational Design of Copper(II)-Uracil Nanoprocessed Coordination Polymers to Improve Their Cytotoxic Activity in Biological Media

2021

This work is focused on the rational structural design of two isostructural Cu(II) nano-coordination polymers (NCPs) with uracil-1-acetic acid (UAcOH) (CP1n) and 5-fluorouracil-1-acetic acid (CP2n). Suitable single crystals for ꭕ-ray diffraction studies of CP1 and CP2 were prepared under hydrothermal conditions, enabling their structural determination as 1D-CP ladder-like polymeric structures. The control of the synthetic parameters allows their processability into water colloids based on nanoplates (CP1n and CP2n). These NCPs are stable in water at physiological pHs for long periods. However, interestingly, CP1n is chemically altered in culture media. These transformations provoke the part…

Materials scienceCell SurvivalPolymersCytotoxicitychemistry.chemical_elementAntineoplastic Agentschemistry.chemical_compoundHydrolysisBiological mediaCoordination ComplexesCell Line TumorMoietyHumansGeneral Materials Science5-fluorouracilIsostructuralCytotoxicityUracilchemistry.chemical_classificationReactive oxygen speciesRational designUracilQuímicaCombinatorial chemistryCopperCoordination polymerschemistryNano-coordination polymersReactive Oxygen SpeciesCopper
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Copper(II)–Thymine Coordination Polymer Nanoribbons as Potential Oligonucleotide Nanocarriers

2016

This is the peer reviewed version of the following article: Vegas, V. G., Lorca, R., Latorre, A., Hassanein, K., Gómez‐García, C. J., Castillo, O., ... & Amo‐Ochoa, P. (2017). Copper (II)–Thymine Coordination Polymer Nanoribbons as Potential Oligonucleotide Nanocarriers. Angewandte Chemie International Edition, 56(4), 987-991, which has been published in final form at https://doi.org/10.1002/anie.201609031. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions

Coordination polymerInorganic chemistrySupramolecular chemistryOligonucleotideschemistry.chemical_element02 engineering and technology010402 general chemistry01 natural sciencesCatalysischemistry.chemical_compoundColloidchemistry.chemical_classificationOligonucleotideNanoribbonsGeneral MedicineGeneral ChemistryPolymerQuímica021001 nanoscience & nanotechnologyCombinatorial chemistryCopper0104 chemical sciencesThymineCoordination polymerschemistryNanocarriers0210 nano-technologyNanocarriers
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CCDC 2064123: Experimental Crystal Structure Determination

2021

Related Article: Verónica G. Vegas, Ana Latorre, María Luisa Marcos, Carlos J. Gómez-García, Óscar Castillo, Félix Zamora, Jacobo Gómez, José Martínez-Costas, Miguel Vázquez López, Álvaro Somoza, Pilar Amo-Ochoa|2021|ACS Applied Materials and Interfaces|13|31|doi:10.1021/acsami.1c11612

Space GroupCrystallographycatena-[(mu-44'-bipyridine)-(mu-5-fluorouracil-1-acetato)-aqua-(5-fluorouracil-1-acetato)-copper(ii) hydrate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2064122: Experimental Crystal Structure Determination

2021

Related Article: Verónica G. Vegas, Ana Latorre, María Luisa Marcos, Carlos J. Gómez-García, Óscar Castillo, Félix Zamora, Jacobo Gómez, José Martínez-Costas, Miguel Vázquez López, Álvaro Somoza, Pilar Amo-Ochoa|2021|ACS Applied Materials and Interfaces|13|31|doi:10.1021/acsami.1c11612

Space GroupCrystallographyCrystal Systemcatena-[(mu-44'-bipyridine)-(mu-uracil-1-acetato)-aqua-(uracil-1-acetato)-copper(ii) trihydrate]Crystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1496195: Experimental Crystal Structure Determination

2017

Related Article: Verónica G. Vegas, Romina Lorca, Ana Latorre, Khaled Hassanein, Carlos J. Gómez-García, Oscar Castillo, Álvaro Somoza, Félix Zamora, Pilar Amo-Ochoa|2017|Angew.Chem.,Int.Ed.|56|987|doi:10.1002/anie.201609031

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterscatena-[aqua-(mu-44'-bipyridine)-bis((5-methyl-24-dioxo-34-dihydropyrimidin-1(2H)-yl)acetato)-copper(ii) dihydrate]Experimental 3D Coordinates
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