0000000001311009
AUTHOR
D. Ott
Magnetic resonance imaging in juvenile Canavan disease
We present a 2-year-old boy and a 6-year-old girl with mild Canavan disease (CD). Aspartoacylase activity in skin fibroblasts was deficient. Magnetic resonance imaging (MRI) of the brain did not show the prominent leucodystrophy previously reported in CD, but there was a hyperintense signal from the lentiform nuclei and the heads of the caudate nuclei on the T2-weighted MR images. This suggests a specific vulnerability of the corpus striatum in these patients. In the older patient, the white matter became affected at the age of 6 years. Proton magnetic resonance spectroscopy (1H-MRS) of white matter revealed a normal concentration of N-acetyl-L-aspartate (NAA) and a markedly decreased conce…
CCDC 640295: Experimental Crystal Structure Determination
Related Article: C.Peifer, D.Ott, D.Schollmeyer, S.Laufer|2007|Acta Crystallogr.,Sect.E:Struct.Rep.Online|63|o1415|doi:10.1107/S1600536807007660