0000000001311009

AUTHOR

D. Ott

showing 2 related works from this author

Magnetic resonance imaging in juvenile Canavan disease

1993

We present a 2-year-old boy and a 6-year-old girl with mild Canavan disease (CD). Aspartoacylase activity in skin fibroblasts was deficient. Magnetic resonance imaging (MRI) of the brain did not show the prominent leucodystrophy previously reported in CD, but there was a hyperintense signal from the lentiform nuclei and the heads of the caudate nuclei on the T2-weighted MR images. This suggests a specific vulnerability of the corpus striatum in these patients. In the older patient, the white matter became affected at the age of 6 years. Proton magnetic resonance spectroscopy (1H-MRS) of white matter revealed a normal concentration of N-acetyl-L-aspartate (NAA) and a markedly decreased conce…

MalePathologymedicine.medical_specialtyMagnetic Resonance SpectroscopyCanavan DiseaseStriatumAmidohydrolasesCholineWhite matterMyelinchemistry.chemical_compoundDegenerative diseasemedicineHumansCholineChildAspartic Acidmedicine.diagnostic_testbusiness.industryBrainMagnetic resonance imagingmedicine.diseaseMagnetic Resonance ImagingCorpus StriatumCanavan diseasemedicine.anatomical_structurenervous systemchemistryChild PreschoolPediatrics Perinatology and Child HealthFemaleAspartoacylase activitybusinessMyelin ProteinsEuropean Journal of Pediatrics
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CCDC 640295: Experimental Crystal Structure Determination

2007

Related Article: C.Peifer, D.Ott, D.Schollmeyer, S.Laufer|2007|Acta Crystallogr.,Sect.E:Struct.Rep.Online|63|o1415|doi:10.1107/S1600536807007660

Ethyl (23-dihydro-1H1'H-23'-biindol-1-yl)glyoxylateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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