0000000001311724
AUTHOR
Tiina Saloranta
From Mannose to Small Amphiphilic Polyol: Perfect Linearity Leads To Spontaneous Aggregation
Terminally unsaturated and diastereochemically pure polyol derived from d-mannose shows spontaneous aggregation behavior in water solution. In order to study and clarify this unforeseen phenomenon, a conformational study based on NMR spectroscopy combined with ab initio structure analysis using the COSMO-solvation model was pursued. The results, together with X-ray diffraction studies, suggest a low energy linear conformation for this particular substrate both in solid states and in solution. For such small-sized acyclic carbohydrate derivatives, the linear conformation appears to be a key prerequisite for the unusual molecular self-assembly reported herein. peerReviewed
CCDC 1406085: Experimental Crystal Structure Determination
Related Article: Tiina Saloranta, Anssi Peuronen, Johannes M. Dieterich, Janne Ruokolainen, Manu Lahtinen, Reko Leino|2016|Cryst.Growth Des.|16|655|doi:10.1021/acs.cgd.5b01135