0000000001312286

AUTHOR

Margarida Meireles

showing 3 related works from this author

Cytotoxicities of Polysubstituted Chlorodicarbonyl(cyclopentadienyl) and (Indenyl)ruthenium Complexes

2013

Polysubstituted cyclopentadienyl and indenyl complexes of ruthenium were synthesized and investigated to elucidate their potential cytotoxic activities. In particular, substituted (indenyl)ruthenium complexes inhibited the proliferation of a panel of human adherent cancer cells with comparable activity to reference agent cisplatin. One of the active compounds exerted a concentration dependent inhibition of cell cycle at G1–S transiton as evidenced by flow cytometry.

Cisplatinmedicine.diagnostic_testStereochemistryOrganic Chemistrychemistry.chemical_elementCell cycleFlow cytometryRutheniumInorganic ChemistryConcentration dependentchemistryCyclopentadienyl complexCancer cellmedicineCytotoxic T cellPhysical and Theoretical Chemistryta116medicine.drugOrganometallics
researchProduct

CCDC 929860: Experimental Crystal Structure Determination

2013

Related Article: Denys Mavrynsky, Jani Rahkila, Daniel Bandarra, Soraia Martins, Margarida Meireles, Maria José Calhorda, Ida J. Kovács, István Zupkó, Mikko M. Hänninen, and Reko Leino|2013|Organometallics|32|3012|doi:10.1021/om400234p

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(eta^5^-47-Dimethyl-123-tris(4-methylbenzyl)-1H-indenyl)-docarbonyl-chloro-rutheniumExperimental 3D Coordinates
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CCDC 929859: Experimental Crystal Structure Determination

2013

Related Article: Denys Mavrynsky, Jani Rahkila, Daniel Bandarra, Soraia Martins, Margarida Meireles, Maria José Calhorda, Ida J. Kovács, István Zupkó, Mikko M. Hänninen, and Reko Leino|2013|Organometallics|32|3012|doi:10.1021/om400234p

Space GroupCrystallography(eta^5^-2-Benzoyloxy-13-diphenyl-1H-cyclopenta[l]phenanthrenyl)-dicarbonyl-chloro-rutheniumCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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