0000000001315402

AUTHOR

V. Pratap Reddy Gajulapalli

showing 2 related works from this author

Organocatalytic Asymmetric Synthesis of 2,3′-Connected Bis-Indolinones by Mannich Reactions of N-Acetylindolin-3-ones with Isatin N-Boc Ketimines

2017

A highly diastereo- and enantioselective Mannich reaction of N-acetylindolin-3-ones with isatin N-Boc ketimines to form 2,3′-connected bis-indolinones is developed employing a low loading of a readily available bifunctional thiourea catalyst. The asymmetric synthesis connects two indolinones via a vic-diamine unit and generates two neighboring stereocenters.

010405 organic chemistryStereochemistryIsatinOrganic ChemistryEnantioselective synthesis010402 general chemistry01 natural sciencesMedicinal chemistryCatalysis0104 chemical sciencesStereocenterchemistry.chemical_compoundchemistryThioureaOrganocatalysisDiamineBifunctionalMannich reactionSynthesis
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CCDC 1543566: Experimental Crystal Structure Determination

2018

Related Article: V. Pratap Reddy Gajulapalli, Ehsan Jafari, Dipti Sankar Kundu, Suruchi Mahajan, Anssi Peuronen, Kari Rissanen, Dieter Enders|2017|Synthesis|49|4986|doi:10.1055/s-0036-1590823

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterst-butyl (1-acetyl-1'-methyl-2'3-dioxo[1'22'3-tetrahydro-1H3'H-[23'-biindole]]-3'-yl)carbamateExperimental 3D Coordinates
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