Crystal and molecular structure of 2,3,6,7-tetramethoxy-9-trichloromethyl-10-carboxymethyl-9,10-dihydroanthracene

Cl3O6C21H21,Mr=475.75, orthorhombic,P212121,a=21.895(3),b=12.101(2), andc=8.237(2) A,V=2182.4(7) A3,Dx=1.45 g cm−3 forZ=4, λ(MoKα)=0.71069 Aμ=3.99 cm−1,F(000) 984, room temperature,R=0.035 for 1877 observed reflections. The molecule exhibits a folded conformation: the dihedral angle between the benzene rings is 28.3(1)°. The central ring is characterized by acis diaxal configuration of hydrogen atoms in the 9, 10 positions, confirming the 13-C NMR results.

One-step synthesis, crystallographic studies and antimicrobial activity of new 4-diazopyrazole derivatives

Summary A number of new 4-diazopyrazole derivatives were prepared by the reaction of 1- R -3-methyl-5(R 1 -substituted)benzamidopyrazoles with a sevenfold excess of nitrous acid in acetic medium. The compounds were tested for activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus faecalis, Listeria monocytogenes, Candida albicans, Candida tropicalis and Paecilomyces varioti . The highest microbial susceptibility was shown by Gram-positive bacteria, with minimum inhibitory concentrations (MIC) in the range 0.5–12.5 μg/mL. For S aureus the R 1 substituents were screened utilizing the Topliss operational scheme. The 4-nitro g…

The yttrium chloride-1,10-phenanthroline interaction: Synthesis and X-ray crystal structure of the complex [Y(OH)(H2O)2(phen)2]2Cl4·2(phen)·MeOH

Abstract Investigations on the reaction between YCl3·H2O and phen (1,10-phenanthroline) led to the isolation of the title compound. The synthesis, IR and X-ray structural characterization are described. The crystal contains centrosymmetric binuclear dications [Y2(phen)4(μ-OH)2(H2O)4]4+, uncoordinated chloride anions, two clathrated phen molecules and a disordered methanol molecule. The yttrium ions are eight-coordinated with square antiprismatic geometry to the nitrogen atoms of two phen molecules, to bridging hydroxyl groups and to two water molecules. The Y ⋯ YI separation in the dimer is 3.651(2)A˚.

ChemInform Abstract: One-Step Synthesis, Crystallographic Studies and Antimicrobial Activity of New 4-Diazopyrazole Derivatives.

Summary A number of new 4-diazopyrazole derivatives were prepared by the reaction of 1- R -3-methyl-5(R 1 -substituted)benzamidopyrazoles with a sevenfold excess of nitrous acid in acetic medium. The compounds were tested for activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus faecalis, Listeria monocytogenes, Candida albicans, Candida tropicalis and Paecilomyces varioti . The highest microbial susceptibility was shown by Gram-positive bacteria, with minimum inhibitory concentrations (MIC) in the range 0.5–12.5 μg/mL. For S aureus the R 1 substituents were screened utilizing the Topliss operational scheme. The 4-nitro g…

ChemInform Abstract: Synthesis, Crystallographic Studies and Biological Evaluation of Some 2-Substituted 3-Indazolyl-4(3H)-quinazolinones and 3-Indazolyl-4(3H)- benzotriazinones.

Synthesis, crystallographic studies and biological evaluation of some 2-substituted 3-indazolyl-4(3H)-quinazolinones and 3-indazolyl-4(3H)-benzotriazinones

CCDC 152558: Experimental Crystal Structure Determination

Related Article: F.Benetollo, G.Bombieri, A.Del Pra, G.Alonzo, N.Bertazzi|2001|Inorg.Chim.Acta|319|49|doi:10.1016/S0020-1693(01)00436-4

CCDC 152559: Experimental Crystal Structure Determination

Related Article: F.Benetollo, G.Bombieri, A.Del Pra, G.Alonzo, N.Bertazzi|2001|Inorg.Chim.Acta|319|49|doi:10.1016/S0020-1693(01)00436-4

CCDC 152557: Experimental Crystal Structure Determination

Related Article: F.Benetollo, G.Bombieri, A.Del Pra, G.Alonzo, N.Bertazzi|2001|Inorg.Chim.Acta|319|49|doi:10.1016/S0020-1693(01)00436-4