0000000001323002

AUTHOR

Doina Catrinoiu

showing 4 related works from this author

Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study

2020

AbstractEvidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, gender and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.

MalePediatricsmedicine.medical_specialtyScienceDiseasesComorbidityDisease030204 cardiovascular system & hematologyCOVID-19 ; Medical research ; Diseases ; Risk factorsAged Aged 80 and over COVID-19 Comorbidity Diabetes Mellitus Ethnicity Female Humans Hypertension Male Middle Aged Obesity Pandemics Risk Factors Romania SARS-CoV-2Article03 medical and health sciencesMedical research0302 clinical medicineDiabetes mellitusDiabetes MellitusEthnicitymedicineHumansObesity030212 general & internal medicinePandemicsAgedAged 80 and overMultidisciplinaryRomaniaSARS-CoV-2business.industryQRCOVID-19Retrospective cohort studyMiddle Agedmedicine.diseaseComorbidityObesityClinical trialRisk factorsHypertensionMedicineFemaleObservational studybusinessKidney disease
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Hydroxychloroquine, COVID ‐19 and diabetes. Why it is a different story

2020

Hydroxychloroquine has been proposed for the cure of the COVID-19 due to its anti-inflammatory and anti-viral action. People with diabetes are more prone to severe outcome if affected by COVID-19 and the use of Hydroxychloroquine might have some benefit in this setting. However, the use of Hydroxychloroquine in diabetes deserves particular attention for its documented hypoglycemic action.

Blood Glucosemedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Endocrinology Diabetes and MetabolismSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINE030209 endocrinology & metabolismGlycemic Control030204 cardiovascular system & hematologySeverity of Illness IndexDiabetes Complications03 medical and health sciences0302 clinical medicineEndocrinologyCommentariesInternal medicineDiabetes mellitusSeverity of illnessDiabetes MellitusInternal MedicinemedicineHyperglycaemiaHumansHypoglycemic AgentsBlood Glucose COVID-19 Diabetes Complications Diabetes Mellitus Glycemic Control Humans Hydroxychloroquine Hypoglycemic Agents SARS-CoV-2 Severity of Illness Index Signal TransductionSARS-CoV-2business.industryDiabetesCOVID-19Hydroxychloroquinemedicine.diseaseCOVID-19 Drug TreatmentACE2 Cardiovascular disease COVID‐19CommentarybusinessHydroxychloroquineSignal Transductionmedicine.drugDiabetes/Metabolism Research and Reviews
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Diabetes and renin-angiotensin-aldosterone system: Implications for covid-19 patients with diabetes treatment management

2020

In the context of the COVID-19 continuous spreading, this paper focuses on the increased risk of diabetic patients regarding the metabolic control and the uncertainties related to SARS-CoV-2 infection. Chronic hyperglycaemia negatively affects the immune system, which triggers an increase of morbidity and mortality for viral infections. A key aspect of COVID-19 resides in the involvement of renin-angiotensin-aldosterone (RAAS) system that causes a cascade of reactions mediated by vasoactive peptides with implications in vasoconstriction, vascular permeability, oxidative stress remodelling and tissue injuries. Activation of RAAS at pulmonary level, is responsible for the local damage. Many q…

010405 organic chemistrybusiness.industry030209 endocrinology & metabolismContext (language use)Vascular permeabilityACEi ARBs COVID-19 Diabetes Of renin-angiotensin-aldosterone system RAAS SARS-CoV-2medicine.diseasemedicine.disease_causeBioinformatics01 natural sciences0104 chemical sciences03 medical and health sciences0302 clinical medicineImmune systemMetabolic control analysisDiabetes mellitusRenin–angiotensin systemmedicineGeneral Pharmacology Toxicology and Pharmaceuticsmedicine.symptombusinessVasoconstrictionOxidative stress
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Data on the age, sex, comorbidities, and location of the COVID-19 fatalities in Romania

2021

This dataset consists of 2 .xlsx spreadsheet and 1 .Rmd R markdown file. These data underlie the related manuscript: "Death by SARS-CoV 2 - a Romanian COVID-19 multi-centre comorbidity study".The related study investigated the relationship between SARS-CoV-2 mortality and underlying medical conditions via an observational, retrospective study based on Romanian official data about location, age, sex and comorbidities for COVID-19 fatalities.The data files are as follows:- Pantea Stoian et al Death by SARS-CoV 2 -PneumoniaCOVID19_data.xlsx: This spreadsheet contains all the data on COVID-19 comorbidities gathered in the related study. The data are de-identified to protect patient privacy.- De…

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