0000000001326533

AUTHOR

Miika Hernelahti

showing 2 related works from this author

Muscle fiber-type distribution predicts weight gain and unfavorable left ventricular geometry: a 19 year follow-up study

2006

Abstract Background Skeletal muscle consists of type-I (slow-twitch) and type-II (fast-twitch) fibers, with proportions highly variable between individuals and mostly determined by genetic factors. Cross-sectional studies have associated low percentage of type-I fibers (type-I%) with many cardiovascular risk factors. Methods We investigated whether baseline type-I% predicts left ventricular (LV) structure and function at 19-year follow-up, and if so, which are the strongest mediating factors. At baseline in 1984 muscle fiber-type distribution (by actomyosin ATPase staining) was studied in 63 healthy men (aged 32–58 years). The follow-up in 2003 included echocardiography, measurement of obes…

Malelcsh:Diseases of the circulatory (Cardiovascular) systemTime Factors030204 cardiovascular system & hematologyDoppler echocardiographyWeight GainBody fat percentageCohort StudiesVentricular Dysfunction Left0302 clinical medicineReference Valuesmedicine.diagnostic_testIncidenceBiopsy NeedleMiddle AgedEchocardiography Dopplermedicine.anatomical_structureMuscle Fibers Slow-TwitchCardiovascular DiseasesMuscle Fibers Fast-TwitchCardiologyRegression Analysismedicine.symptomCardiology and Cardiovascular MedicineResearch ArticleAdultmedicine.medical_specialtyWaistRisk AssessmentSensitivity and Specificity03 medical and health sciencesAge DistributionPredictive Value of TestsInternal medicineHeart ratemedicineHumansObesityMuscle SkeletalAngiologyAgedProbabilityRetrospective Studiesbusiness.industrySkeletal muscle030229 sport sciencesMyocardial ContractionBlood pressurelcsh:RC666-701businessWeight gainFollow-Up StudiesBMC Cardiovascular Disorders
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Muscle fiber-type distribution predicts weight gain and unfavourable left ventricular geometry: a 19 year follow-up study

2006

BACKGROUND: Skeletal muscle consists of type-I (slow-twitch) and type-II (fast-twitch) fibers, with proportions highly variable between individuals and mostly determined by genetic factors. Cross-sectional studies have associated low percentage of type-I fibers (type-I%) with many cardiovascular risk factors. METHODS: We investigated whether baseline type-I% predicts left ventricular (LV) structure and function at 19-year follow-up, and if so, which are the strongest mediating factors. At baseline in 1984 muscle fiber-type distribution (by actomyosin ATPase staining) was studied in 63 healthy men (aged 32–58 years). The follow-up in 2003 included echocardiography, measurement of obesity rel…

obesitysydänlihavuusphysical activityheartliikuntamuscle fiber-typelihassolu
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