Quality evaluation of software architecture with application to OpenH.323 protocol

Master's Thesis in Information Technology 3rd October 2006 The requirements towards software systems usually go beyond the correct functionality, the presence of certain quality demands are also very essential for the systems' acceptance by the stakeholders. So quality control and management must be carried out through the whole development process to ensure the implementation of required quality characteristics. This thesis focuses on the quality control of the software architecture. Several approaches for evaluating the architecture are presented. Furthermore the OpenH.323 protocol architecture is evaluated in a case study. That software architecture is evaluated with two approaches: Arch…

Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients: The Phase III GMMG-HD7 Trial

Abstract Background: In newly-diagnosed multiple myeloma (NDMM), lenalidomide/bortezomib/dexamethasone (RVd) is one of the most widely used combination regimens. Anti-CD38 monoclonal antibodies (CD38-moAb) increase efficacy when added to standard-of-care regimens. Here we present the first primary endpoint of the randomized, open-label, multicenter, phase III GMMG-HD7 trial, comparing RVd without (arm IA) or with the CD38-moAb isatuximab (Isa, arm IB) with regard to the rate of minimal residual disease (MRD) negativity after induction therapy in patients with transplant-eligible NDMM. Patients and Methods: Patients with transplant-eligible NDMM at 67 sites in Germany were equally randomized…

Evaluation Practices in Architecture Work

Architecture Evaluation Methods

AISA Project report. Originally published 2.5.2007