0000000001326989
AUTHOR
M Alberghina
In vitro models of blood-brain barrier set by co-culturing primary pericytes, astrocytes and brain capillary endothelial cells
The blood-brain barrier (BBB) is formed by brain capillary endothelial cells (BCECs) under the effects of the brain microenvironment. BCECs are sealed together by tight junctions (TJs) [2]. We previously found that occludin, one of the main TJ components, is correctly localized at the cell periphery only if BCECs are co-cultured with neurons/astrocytes [1-2]. Moreover, pericytes induce PLA2 protein expression through activation of PKCalpha and the MAPK/ERK cascade in immortalized GP8.3 endothelial cells [3]. In the present work, we analyzed the effects of pericytes and/or astrocytes on survival and differentiation of primary endothelial cells, in the presence of a serum-free medium. To test…
Archaeometric characterization and 3D survey: new perspectives for monitoring and valorization of Morgantina silver Treasure (Sicily)
The Morgantina silver Treasure belonging to the collections of the Archaeological Museum of Aidone (Sicily) were involved in a 3D survey and diagnostics campaign for monitoring over time of the finds, in anticipation of their temporary transfer to the Metropolitan Museum of Art in New York, for a period of four years. According to a multidisciplinary approach, it has been developed a scientific and methodological protocol based on non-invasive techniques to achieve a complete and integrated knowledge of the precious items, of their conservation state and increasing their valorisation. All acquired data, i.e. 3D models, UV fluorescence and X-Ray images and chemical information, will be made …
Atti del Workshop: Tecniche Speciali e Avanzate di Dosimetria e Radioprotezione
Atti del Workshop organizzato dall'Associazione Italiana di Radioprotezione (AIRP) in collaborazione con l'Università degli Studi di Palermo, dal titolo "Tecniche Speciali e Avanzate in Dosimetria e Radioprotezione" che si svolgerà venerdì 24 Giugno a Palermo presso l'Aula Magna del Dipartimento di Fisica e Chimica, Viale delle Scienze Edificio 18. L'evento rientra tra i 210 Eventi organizzati per i 210 anni dalla fondazione dell'Ateneo palermitano su iniziativa del Magnifico Rettore, Prof. Fabrizio Micari. L’evento prevede la discussione di 4 tematiche in ambito della dosimetria e della radioprotezione in campo sanitario ed ambientale (Dosimetria Clinica, Dosimetria Ambientale, Dosimetria …