6533b7cefe1ef96bd125706c
RESEARCH PRODUCT
Body mass index as a predictor of all-cause mortality in nursing home residents during a 5-year follow-up.
Elena Debora ToffanelloEnzo ManzatoAlessandra CoinFabrizio CardinB DavanzoFrancesco BolzettaNicola VeroneseGiuseppe SergiMarina De RuiEgle PerissinottoIrene De Ronchsubject
GerontologyMaleLongitudinal studyComorbiditySeverity of Illness IndexBody Mass IndexPredictive Value of TestsCause of DeathMedicineHumansLongitudinal StudiesBody mass index nursing home mortality elderly nutritionGeriatric AssessmentGeneral NursingSurvival analysisCause of deathAgedProportional Hazards ModelsAged 80 and overbusiness.industryProportional hazards modelHealth PolicyMortality rateGeneral Medicinemedicine.diseaseComorbidityNursing HomesPredictive value of testsLinear ModelsFemaleGeriatrics and GerontologybusinessBody mass indexDemographyFollow-Up Studiesdescription
Background: Body mass index (BMI) is considered a short-term mortality predictor, but a consensus has not been reached on its role and that of other nutritional parameters in predicting long-term mortality in nursing home residents. Objectives: To correlate BMI, Mini Nutritional Assessment scores, and serum albumin levels with the 5-year mortality rate in institutionalized elderly subjects. Methods: A total of 181 nursing home residents aged ≥70 years were included in a 5-year longitudinal study. Data were collected on all participants' nutritional, health, cognitive, and functional status by means of a comprehensive geriatric assessment. Data on the participants' vital status were obtained 5 years after beginning the study, and a survival analysis was conducted using Kaplan-Meier curves and multivariate Cox proportional hazards models. Results: The 5-year mortality rate was 63%. The deceased subjects (n = 115) had a lower BMI (24.7 ± 4.6 vs 26.6 ± 5.0 kg/m2; P = .03) and Mini Nutritional Assessment score (18.6 ± 3.7 vs 20.1 ± 3.6; P = .02) than those still alive. Serum albumin levels did not differ between the two groups. Among the three indicators of nutritional status considered in this study, only BMI ≥ 30 kg/m2 was significantly associated with a lower mortality risk at 5 years (hazard ratio = 0.432; 95% CI 0.20-0.70; P = .04), the risk for death being greater the lower the BMI class (log-rank test: P < .001). Conclusions: Our findings suggest that BMI is the best of the three parameters considered as a nutritional predictor of nursing home residents' mortality in the longer term, and indicate that a lower mortality risk coincides with a higher BMI. © 2013 American Medical Directors Association, Inc.
year | journal | country | edition | language |
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2013-01-01 | Journal of the American Medical Directors Association |