6533b7cefe1ef96bd125714a
RESEARCH PRODUCT
Response to 'Thyrocytes — not innocent bystanders in autoimmune disease'
Ruggero De MariaGiorgio Stassisubject
Lymphocytic InfiltrateAutoimmune diseaseImmunologyImmunologymedicineImmunology and AllergyBiologymedicine.diseasePhenotypeFas liganddescription
Giordano et al. propose that thyrocytes play a crucial role in the regulation of the autoimmune response during GD. According to them, Fas is weakly expressed in GD thyrocytes, whereas FasL is responsible for a specific deletion of infiltrating TH1 cells and maintains a TH2 phenotype in the lymphocytic infiltrate.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-03-01 | Nature Immunology |