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RESEARCH PRODUCT
A case of visceral leishmaniasis and pulmonary tuberculosis in a post-partum woman
Manlio TolomeoMassimo CajozzoClaudia ColombaLucia AdamoliMarcello TrizzinoLucia SiracusaSilvia BonuraGiovanni M. Giammancosubject
Microbiology (medical)AdultSettore MED/07 - Microbiologia E Microbiologia ClinicaCellular immunityTuberculosisSettore MED/17 - Malattie Infettivelcsh:Infectious and parasitic diseasesYoung AdultPulmonary TuberculosisImmune systemImmunityPregnancyparasitic diseasesPulmonary TuberculosiMedicineHumanslcsh:RC109-216Leishmania infantumTuberculosis PulmonaryVisceral leishmaniasisVisceral leishmaniasibiologybusiness.industryCoinfectionPostpartum PeriodLeishmaniasisGeneral Medicinebiology.organism_classificationmedicine.diseasePregnancy ComplicationsInfectious DiseasesVisceral leishmaniasisHumoral immunityImmunologyLeishmaniasis VisceralFemaleLeishmania infantumbusinessdescription
AbstractVisceral leishmaniasis due to Leishmania infantum is a vector-borne zoonotic disease transmitted by sand fly bites endemic in rural or periurban areas of the Mediterranean basin. Pregnancy is accompanied by changes in immune response, mainly a decrease in cellular immunity and a proportional increase in humoral immunity. These physiological events result in increased risk of infection by pathogens whose immunity is based on a T-helper 1 predominant response. We describe a case of visceral leishmaniasis and pulmonary tuberculosis diagnosed in a post-partum woman four days after delivery. The diagnosis of leishmaniasis should be considered in pregnant women with fever and haematologic abnormalities in endemic regions or if a history of exposure in endemic areas is reported.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-04-01 | International Journal of Infectious Diseases |