The evolving role of platelets in inflammation.

6533b7cefe1ef96bd12572b3

RESEARCH PRODUCT

The evolving role of platelets in inflammation.

Guy A. Zimmerman Andrew S. Weyrich Stephan Lindemann

subject

Blood Platelets Inflammation Integrins Inflammation Translation (biology)Thrombosis Hematology Molecular systems Biology Platelet Activation Cell biology medicine Humans Platelet Platelet activation medicine.symptom Phylogeny

description

Platelets are small in size and simple in structure. Nevertheless, these anucleate cytoplasts utilize complex molecular systems to regulate a variety of biological functions. Here we review evolutionary paths, traditional roles, and previously unrecognized biological capacities of platelets that interface thrombosis with inflammation and potentially identify new roles in inflammatory diseases.

year	journal	country	edition	language
2003-08-28	Journal of thrombosis and haemostasis : JTH

10.1046/j.1538-7836.2003.00304.x https://pubmed.ncbi.nlm.nih.gov/12941029

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