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RESEARCH PRODUCT

Ticlopidine in the Treatment of Multiple Atherosclerotic Arteriopathy: a Strain Gauge Plethysmography and Döppler Spectrum Analysis Evaluation

Francesco MeliGlauco MilioV. ScrivanoMichele CospiteFilippo Ferrara

subject

medicine.medical_specialtyPathologyTiclopidineArteriosclerosisCervical ArteryHemodynamics030204 cardiovascular system & hematologyBiochemistry03 medical and health sciencessymbols.namesake0302 clinical medicineInternal medicineHumansMedicinePlethysmograph030212 general & internal medicineTiclopidineFlunarizineAgedUltrasonographybusiness.industryVascular diseaseBiochemistry (medical)Cell BiologyGeneral MedicineMiddle Agedmedicine.diseasePlethysmographyCardiologysymbolsbusinessDoppler effectBlood Flow VelocityFlunarizinemedicine.drugStrain gauge plethysmography

description

The effect of ticlopidine was compared with flunarizine in patients with iliac–femoral and / or femoral–popliteal arteriosclerotic arteriopathy accompanied by lesions of the cervical arteries of no haemodynamic significance. In the lower limbs, plethysmography (strain gauge measurements) and Döppler ultrasonography integrated by spectral analysis of the cervical arteries showed qualitative and quantitative improvements of the regional haematic flow. Side-effects were negligible which suggests that ticlopidine is useful in the treatment of multiple arteriosclerotic arteriopathy.

https://doi.org/10.1177/030006058701500506