6533b7cefe1ef96bd1257aea

RESEARCH PRODUCT

Clinical and histopathological study of the oral multifocal melanoacanthoma : a case report

Jozinete-vieira PereiraDaliana Queiroga De Castro GomesPollianna Muniz AlvesIngrid-morgana-fernandes GonçalvesCassiano-francisco-weege Nonaka

subject

medicine.medical_specialtyMucocutaneous zoneCase Report030209 endocrinology & metabolismLesion03 medical and health sciences0302 clinical medicinestomatognathic systemmedicineNevusOral mucosaGeneral DentistryOral Medicine and Pathologybusiness.industryMelanomaAmalgam tattoo030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDermatologyMelanoacanthomastomatognathic diseasesmedicine.anatomical_structureUNESCO::CIENCIAS MÉDICASmedicine.symptomDifferential diagnosisbusiness

description

Melanoacanthoma is a blackened mucocutaneous lesion, mainly affecting individuals with dark skin and exhibiting rapid development. Differential diagnosis includes nevus, amalgam tattoo and melanoma. This article reports a case of a 53-year-old white woman, who exhibited multiple blackened lesions on the gingiva and upper lip. After incisional biopsy, the presence of numerous melanin-containing dendritic cells distributed throughout the epithelial thickness, which were S-100 (+), were observed microscopically. Final diagnosis was multifocal oral melanoacanthoma. Follow-up for 28 months has shown appearing of more lesions in gingiva and upper lip. Therefore, the importance of differential diagnosis of oral melanoma with the group of oral pigmented lesions, and possible associated systemic diseases were evaluated. Key words:Melanocytes, pigmentation, oral mucosa, gingiva, differential diagnosis.

yearjournalcountryeditionlanguage
2019-04-01
10.4317/jced.55344https://hdl.handle.net/10550/70648