6533b7cffe1ef96bd125837c
RESEARCH PRODUCT
On the enhancement of stereoselection by cooperation between chiral auxiliaries. Asymmetric diels-alder reactions with fumaric acid bis ((S)-proline benzyl ester) amide
Martin DrägerHerbert Waldmannsubject
Fumaric acidCyclopentadieneOrganic ChemistryDiastereomerBiochemistryCatalysischemistry.chemical_compoundchemistryAmideDrug DiscoveryDiels alderOrganic chemistryLewis acids and basesProline benzyl esterdescription
Abstract Fumaric acid bis ((S)-proline benzyl ester) amide reacts with cyclopentadiene in thermal and Lewis acid catalyzed Diels-Alder reactions to give the cycloadducts with high yields and diastereomeric ratios up to 100:1.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1989-01-01 | Tetrahedron Letters |