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RESEARCH PRODUCT

The Role of Vitamin D in Early Knee Osteoarthritis and Its Relationship with Their Physical and Psychological Status

Joaquin CalatayudLuz Herrero-manleyFerran Cuenca-martínezLuis Suso-martíClovis Varangot-reilleMaría Blanco-diazEnrique Viosca-herreroAna Alabajos-ceaJosé Casaña

subject

AdultMalemedicine.medical_specialtyVitaminesParathyroid hormonevitamin DDiseaseOsteoarthritisArtrosiGastroenterologyArticle03 medical and health sciences0302 clinical medicinePsychological statusInternal medicinemedicineVitamin D and neurologyHumansTX341-641030212 general & internal medicinePain MeasurementNutrition and DieteticsGenollsbusiness.industryNutrition. Foods and food supplyMiddle AgedOsteoarthritis KneeVitamin D Deficiencymedicine.diseasePreferred walking speedosteoarthritisCross-Sectional StudiesParathyroid HormoneAnxietyFemalemedicine.symptombusinessearly osteoarthritis030217 neurology & neurosurgeryFood ScienceEarly osteoarthritis

description

Osteoarthritis (OA) is a common joint condition and one of the greatest causes of disability worldwide. The role of vitamin D in the origin and development of the disease is not clear, although it could have important implications for diagnosis and treatment. For this proposal, a cross-sectional study with a non-probabilistic sample was performed. In total, 48 with early osteoarthritis (EOA) and 48 matched controls were selected, and serum 25(OH)D and parathyroid hormone (PTH) levels were analyzed. In addition, physical and psychological variables were measured to establish their relationship with vitamin D levels. Patients with EOA showed lower levels (22.3 ± 7.3 ng/mL) in comparison to matched controls (29.31 ± 9.2 ng/mL). A statistically significant higher number (Chi-squared = 8.525

10.3390/nu13114035https://www.mdpi.com/2072-6643/13/11/4035