6533b7cffe1ef96bd1258700
RESEARCH PRODUCT
Stimuli-responsive bile acid-based metallogels forming in aqueous media
Elina KaleniusKatri ToikkanenRiikka KuosmanenVirpi NoponenHannu SaloElina Sievänensubject
medicine.drug_classSonicationClinical BiochemistryConjugated systemPicolinic acidBiochemistrystimuli-responsiveBile Acids and Saltschemistry.chemical_compoundpicolinic acidEndocrinologyAcetonemedicineOrganic chemistrybile acidPicolinic AcidsAcetonitrileMolecular Biologyta116PharmacologyMolecular StructureBile acidOrganic Chemistryself-assemblyAmideschemistrySelf-assemblymetallogelGelsCopperDerivative (chemistry)description
Abstract The synthesis and gelation properties of a picolinic acid conjugated bile acid derivative in the presence of metal salts along with the stimuli-responsiveness of the systems are reported. The gels are formed in the presence of Cu 2+ ions in the solvent systems composed of 30–50% of organic solvent (MeOH, acetonitrile, or acetone) in water. The gels respond to various stimuli: they can be formed upon sonication or shaking, and their gel–sol transformation can be triggered by a variety of chemical species. NMR, MS, and SEM techniques are exploited in order to gain a deeper insight on the self-assembled systems.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-05-01 | Steroids |